| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OsmY_3 | diaA | HMPREF0758_1883 | HMPREF0758_1884 | Phospholipid-binding domain protein; COG: COG2823; Pfam: PF04972; InterPro: IPR007055. | DnaA initiator-associating protein DiaA; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | 0.780 |
| OsmY_3 | lpoA | HMPREF0758_1883 | HMPREF0758_1886 | Phospholipid-binding domain protein; COG: COG2823; Pfam: PF04972; InterPro: IPR007055. | LppC; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family. | 0.609 |
| OsmY_3 | yraL | HMPREF0758_1883 | HMPREF0758_1887 | Phospholipid-binding domain protein; COG: COG2823; Pfam: PF04972; InterPro: IPR007055. | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.457 |
| OsmY_3 | yraN | HMPREF0758_1883 | HMPREF0758_1885 | Phospholipid-binding domain protein; COG: COG2823; Pfam: PF04972; InterPro: IPR007055. | TIGR00252 family protein; COG: COG0792; Pfam: PF02021; InterPro: IPR003509; Belongs to the UPF0102 family. | 0.617 |
| comF | comM | HMPREF0758_1051 | HMPREF0758_1136 | comF family protein; COG: COG1040; Pfam: PF00156. | Mg chelatase-like protein; COG: COG0606; Pfam: PF01078; InterPro: IPR004482. | 0.850 |
| comF | dprA | HMPREF0758_1051 | HMPREF0758_0927 | comF family protein; COG: COG1040; Pfam: PF00156. | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | 0.928 |
| comF | rec | HMPREF0758_1051 | HMPREF0758_4381 | comF family protein; COG: COG1040; Pfam: PF00156. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.826 |
| comF | yraN | HMPREF0758_1051 | HMPREF0758_1885 | comF family protein; COG: COG1040; Pfam: PF00156. | TIGR00252 family protein; COG: COG0792; Pfam: PF02021; InterPro: IPR003509; Belongs to the UPF0102 family. | 0.695 |
| comM | comF | HMPREF0758_1136 | HMPREF0758_1051 | Mg chelatase-like protein; COG: COG0606; Pfam: PF01078; InterPro: IPR004482. | comF family protein; COG: COG1040; Pfam: PF00156. | 0.850 |
| comM | dprA | HMPREF0758_1136 | HMPREF0758_0927 | Mg chelatase-like protein; COG: COG0606; Pfam: PF01078; InterPro: IPR004482. | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | 0.854 |
| comM | rec | HMPREF0758_1136 | HMPREF0758_4381 | Mg chelatase-like protein; COG: COG0606; Pfam: PF01078; InterPro: IPR004482. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.598 |
| comM | yraN | HMPREF0758_1136 | HMPREF0758_1885 | Mg chelatase-like protein; COG: COG0606; Pfam: PF01078; InterPro: IPR004482. | TIGR00252 family protein; COG: COG0792; Pfam: PF02021; InterPro: IPR003509; Belongs to the UPF0102 family. | 0.525 |
| diaA | OsmY_3 | HMPREF0758_1884 | HMPREF0758_1883 | DnaA initiator-associating protein DiaA; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | Phospholipid-binding domain protein; COG: COG2823; Pfam: PF04972; InterPro: IPR007055. | 0.780 |
| diaA | lpoA | HMPREF0758_1884 | HMPREF0758_1886 | DnaA initiator-associating protein DiaA; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | LppC; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family. | 0.695 |
| diaA | yraL | HMPREF0758_1884 | HMPREF0758_1887 | DnaA initiator-associating protein DiaA; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.486 |
| diaA | yraN | HMPREF0758_1884 | HMPREF0758_1885 | DnaA initiator-associating protein DiaA; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | TIGR00252 family protein; COG: COG0792; Pfam: PF02021; InterPro: IPR003509; Belongs to the UPF0102 family. | 0.718 |
| dprA | comF | HMPREF0758_0927 | HMPREF0758_1051 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | comF family protein; COG: COG1040; Pfam: PF00156. | 0.928 |
| dprA | comM | HMPREF0758_0927 | HMPREF0758_1136 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | Mg chelatase-like protein; COG: COG0606; Pfam: PF01078; InterPro: IPR004482. | 0.854 |
| dprA | rec | HMPREF0758_0927 | HMPREF0758_4381 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.881 |
| dprA | yraN | HMPREF0758_0927 | HMPREF0758_1885 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | TIGR00252 family protein; COG: COG0792; Pfam: PF02021; InterPro: IPR003509; Belongs to the UPF0102 family. | 0.563 |