| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ftsZ | metG | HMPREF0758_0508 | HMPREF0758_4580 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.545 |
| ftsZ | yraL | HMPREF0758_0508 | HMPREF0758_1887 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.679 |
| gidB | metG | HMPREF0758_1325 | HMPREF0758_4580 | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.626 |
| gidB | rlmH | HMPREF0758_1325 | HMPREF0758_4915 | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.549 |
| gidB | rsmF | HMPREF0758_1325 | HMPREF0758_4017 | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.404 |
| gidB | yraL | HMPREF0758_1325 | HMPREF0758_1887 | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.537 |
| lpoA | yraL | HMPREF0758_1886 | HMPREF0758_1887 | LppC; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family. | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.584 |
| lpoA | yraN | HMPREF0758_1886 | HMPREF0758_1885 | LppC; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family. | TIGR00252 family protein; COG: COG0792; Pfam: PF02021; InterPro: IPR003509; Belongs to the UPF0102 family. | 0.840 |
| metG | ftsZ | HMPREF0758_4580 | HMPREF0758_0508 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.545 |
| metG | gidB | HMPREF0758_4580 | HMPREF0758_1325 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.626 |
| metG | yraL | HMPREF0758_4580 | HMPREF0758_1887 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.530 |
| rlmH | gidB | HMPREF0758_4915 | HMPREF0758_1325 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.549 |
| rlmH | rsmF | HMPREF0758_4915 | HMPREF0758_4017 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.416 |
| rlmH | yraL | HMPREF0758_4915 | HMPREF0758_1887 | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.510 |
| rnhB | yraL | HMPREF0758_2345 | HMPREF0758_1887 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.525 |
| rsmF | gidB | HMPREF0758_4017 | HMPREF0758_1325 | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.404 |
| rsmF | rlmH | HMPREF0758_4017 | HMPREF0758_4915 | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.416 |
| rsmF | yraL | HMPREF0758_4017 | HMPREF0758_1887 | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.529 |
| smtA3 | yhbQ | HMPREF0758_2445 | HMPREF0758_0786 | Methyltransferase small domain protein; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | GIY-YIG catalytic domain protein; COG: COG2827; Pfam: PF01541; InterPro: IPR000305. | 0.604 |
| smtA3 | yraL | HMPREF0758_2445 | HMPREF0758_1887 | Methyltransferase small domain protein; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.599 |