| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE95393.1 | Fre | HMPREF0758_3084 | HMPREF0758_1643 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | FMN reductase; COG: COG0543; Pfam: PF00970,PF00175; InterPro: IPR001433. | 0.427 |
| EFE95393.1 | fadB | HMPREF0758_3084 | HMPREF0758_1645 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.578 |
| EFE95393.1 | fadH | HMPREF0758_3084 | HMPREF0758_1911 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785. | 0.715 |
| EFE95393.1 | fadJ | HMPREF0758_3084 | HMPREF0758_2723 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | Fatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.578 |
| EFE95393.1 | gltB | HMPREF0758_3084 | HMPREF0758_1877 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.433 |
| EFE95393.1 | hcr | HMPREF0758_3084 | HMPREF0758_4466 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | 0.601 |
| EFE95393.1 | paaK | HMPREF0758_3084 | HMPREF0758_3095 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | phenylacetate-CoA oxygenase/reductase, PaaK subunit; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR011884. | 0.731 |
| Fre | EFE95393.1 | HMPREF0758_1643 | HMPREF0758_3084 | FMN reductase; COG: COG0543; Pfam: PF00970,PF00175; InterPro: IPR001433. | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | 0.427 |
| Fre | fadH | HMPREF0758_1643 | HMPREF0758_1911 | FMN reductase; COG: COG0543; Pfam: PF00970,PF00175; InterPro: IPR001433. | Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785. | 0.823 |
| Fre | hcr | HMPREF0758_1643 | HMPREF0758_4466 | FMN reductase; COG: COG0543; Pfam: PF00970,PF00175; InterPro: IPR001433. | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | 0.573 |
| Fre | paaK | HMPREF0758_1643 | HMPREF0758_3095 | FMN reductase; COG: COG0543; Pfam: PF00970,PF00175; InterPro: IPR001433. | phenylacetate-CoA oxygenase/reductase, PaaK subunit; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR011884. | 0.447 |
| GltB_2 | fadH | HMPREF0758_4629 | HMPREF0758_1911 | Glutamate synthase domain protein; COG: COG0069; Pfam: PF01645; InterPro: IPR002932; Belongs to the glutamate synthase family. | Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785. | 0.902 |
| GltB_2 | gltB | HMPREF0758_4629 | HMPREF0758_1877 | Glutamate synthase domain protein; COG: COG0069; Pfam: PF01645; InterPro: IPR002932; Belongs to the glutamate synthase family. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.952 |
| fadB | EFE95393.1 | HMPREF0758_1645 | HMPREF0758_3084 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | 0.578 |
| fadB | fadH | HMPREF0758_1645 | HMPREF0758_1911 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785. | 0.804 |
| fadB | fadJ | HMPREF0758_1645 | HMPREF0758_2723 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | Fatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.973 |
| fadB | gltB | HMPREF0758_1645 | HMPREF0758_1877 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.570 |
| fadB | hcr | HMPREF0758_1645 | HMPREF0758_4466 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | 0.555 |
| fadB | paaK | HMPREF0758_1645 | HMPREF0758_3095 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | phenylacetate-CoA oxygenase/reductase, PaaK subunit; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR011884. | 0.555 |
| fadH | EFE95393.1 | HMPREF0758_1911 | HMPREF0758_3084 | Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785. | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | 0.715 |