| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RfaF_2 | RfaQ_1 | HMPREF0758_1252 | HMPREF0758_1255 | Heptosyltransferase; Pfam: PF01075; InterPro: IPR002201. | Putative lipopolysaccharide heptosyltransferase III; COG: COG0859; Pfam: PF01075; InterPro: IPR011916. | 0.872 |
| RfaF_2 | diaA | HMPREF0758_1252 | HMPREF0758_1884 | Heptosyltransferase; Pfam: PF01075; InterPro: IPR002201. | DnaA initiator-associating protein DiaA; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | 0.741 |
| RfaF_2 | gmhA | HMPREF0758_1252 | HMPREF0758_0334 | Heptosyltransferase; Pfam: PF01075; InterPro: IPR002201. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.750 |
| RfaF_2 | gmhB | HMPREF0758_1252 | HMPREF0758_2369 | Heptosyltransferase; Pfam: PF01075; InterPro: IPR002201. | D,D-heptose 1,7-bisphosphate phosphatase; COG: COG0241; Pfam: PF00702; InterPro: IPR004446. | 0.754 |
| RfaF_2 | kdsD2 | HMPREF0758_1252 | HMPREF0758_1856 | Heptosyltransferase; Pfam: PF01075; InterPro: IPR002201. | Sugar isomerase, KpsF/GutQ family; COG: COG0794; Pfam: PF01380,PF00571; InterPro: IPR004800. | 0.420 |
| RfaF_2 | rfaC | HMPREF0758_1252 | HMPREF0758_1248 | Heptosyltransferase; Pfam: PF01075; InterPro: IPR002201. | Lipopolysaccharide heptosyltransferase I; COG: COG0859; Pfam: PF01075; InterPro: IPR011908. | 0.659 |
| RfaF_2 | rfaD | HMPREF0758_1252 | HMPREF0758_1246 | Heptosyltransferase; Pfam: PF01075; InterPro: IPR002201. | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.524 |
| RfaF_2 | rfaE | HMPREF0758_1252 | HMPREF0758_1943 | Heptosyltransferase; Pfam: PF01075; InterPro: IPR002201. | Bifunctional protein RfaE, domain I; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.783 |
| RfaF_2 | rfaF | HMPREF0758_1252 | HMPREF0758_1247 | Heptosyltransferase; Pfam: PF01075; InterPro: IPR002201. | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 0.612 |
| RfaQ_1 | RfaF_2 | HMPREF0758_1255 | HMPREF0758_1252 | Putative lipopolysaccharide heptosyltransferase III; COG: COG0859; Pfam: PF01075; InterPro: IPR011916. | Heptosyltransferase; Pfam: PF01075; InterPro: IPR002201. | 0.872 |
| RfaQ_1 | RfaQ_2 | HMPREF0758_1255 | HMPREF0758_1258 | Putative lipopolysaccharide heptosyltransferase III; COG: COG0859; Pfam: PF01075; InterPro: IPR011916. | Heptosyltransferase; Pfam: PF01075; InterPro: IPR002201. | 0.929 |
| RfaQ_1 | diaA | HMPREF0758_1255 | HMPREF0758_1884 | Putative lipopolysaccharide heptosyltransferase III; COG: COG0859; Pfam: PF01075; InterPro: IPR011916. | DnaA initiator-associating protein DiaA; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | 0.674 |
| RfaQ_1 | gmhA | HMPREF0758_1255 | HMPREF0758_0334 | Putative lipopolysaccharide heptosyltransferase III; COG: COG0859; Pfam: PF01075; InterPro: IPR011916. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.685 |
| RfaQ_1 | gmhB | HMPREF0758_1255 | HMPREF0758_2369 | Putative lipopolysaccharide heptosyltransferase III; COG: COG0859; Pfam: PF01075; InterPro: IPR011916. | D,D-heptose 1,7-bisphosphate phosphatase; COG: COG0241; Pfam: PF00702; InterPro: IPR004446. | 0.646 |
| RfaQ_1 | kdsD2 | HMPREF0758_1255 | HMPREF0758_1856 | Putative lipopolysaccharide heptosyltransferase III; COG: COG0859; Pfam: PF01075; InterPro: IPR011916. | Sugar isomerase, KpsF/GutQ family; COG: COG0794; Pfam: PF01380,PF00571; InterPro: IPR004800. | 0.516 |
| RfaQ_1 | rfaC | HMPREF0758_1255 | HMPREF0758_1248 | Putative lipopolysaccharide heptosyltransferase III; COG: COG0859; Pfam: PF01075; InterPro: IPR011916. | Lipopolysaccharide heptosyltransferase I; COG: COG0859; Pfam: PF01075; InterPro: IPR011908. | 0.966 |
| RfaQ_1 | rfaD | HMPREF0758_1255 | HMPREF0758_1246 | Putative lipopolysaccharide heptosyltransferase III; COG: COG0859; Pfam: PF01075; InterPro: IPR011916. | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.583 |
| RfaQ_1 | rfaE | HMPREF0758_1255 | HMPREF0758_1943 | Putative lipopolysaccharide heptosyltransferase III; COG: COG0859; Pfam: PF01075; InterPro: IPR011916. | Bifunctional protein RfaE, domain I; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.745 |
| RfaQ_1 | rfaF | HMPREF0758_1255 | HMPREF0758_1247 | Putative lipopolysaccharide heptosyltransferase III; COG: COG0859; Pfam: PF01075; InterPro: IPR011916. | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 0.973 |
| RfaQ_2 | RfaQ_1 | HMPREF0758_1258 | HMPREF0758_1255 | Heptosyltransferase; Pfam: PF01075; InterPro: IPR002201. | Putative lipopolysaccharide heptosyltransferase III; COG: COG0859; Pfam: PF01075; InterPro: IPR011916. | 0.929 |