STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exbBtonB-system energizer ExbB; COG: COG0811; Pfam: PF01618; InterPro: IPR014164. (317 aa)    
Predicted Functional Partners:
exbD
TonB system transport protein ExbD; COG: COG0848; Pfam: PF02472; InterPro: IPR003400.
 
 
 0.999
ExbD_1
Transport energizing protein, ExbD/TolR family; COG: COG0848; Pfam: PF02472; InterPro: IPR003400.
 
 
 0.994
TonB
TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.988
tolR
Putative protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
 
 0.978
tolB
Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
 
  
 0.877
fhuA
TonB-dependent siderophore receptor; COG: COG1629; Pfam: PF07715,PF00593; InterPro: IPR010105.
 
  
 0.783
fes
Putative esterase; COG: COG2382; Pfam: PF00756; InterPro: IPR000801.
   
  
 0.770
tonB
TonB family domain protein.
  
 
 0.749
pal
Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
   
 0.709
fepB
Periplasmic binding protein; COG: COG4592; Pfam: PF01497; InterPro: IPR002491.
   
  
 0.693
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.