STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exbBtonB-system energizer ExbB; COG: COG0811; Pfam: PF01618; InterPro: IPR014164. (317 aa)    
Predicted Functional Partners:
exbD
TonB system transport protein ExbD; COG: COG0848; Pfam: PF02472; InterPro: IPR003400.
 
 
 0.996
ExbD_1
Transport energizing protein, ExbD/TolR family; COG: COG0848; Pfam: PF02472; InterPro: IPR003400.
 
 
 0.955
tolR
Putative protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
 
 0.925
TonB
TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.892
tolB
Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
 
  
 0.725
pal
Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
   
 0.696
fhuA
TonB-dependent siderophore receptor; COG: COG1629; Pfam: PF07715,PF00593; InterPro: IPR010105.
 
  
 0.681
lolC
Lipoprotein releasing system, transmembrane protein, LolC/E family; COG: COG4591; Pfam: PF02687; InterPro: IPR011925.
 
    0.659
lolE
Lipoprotein releasing system, transmembrane protein LolE; COG: COG4591; Pfam: PF02687; InterPro: IPR011925.
 
    0.657
tonB
TonB family domain protein.
  
 
 0.650
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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