| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ExbB_1 | TonB | HMPREF0758_0664 | HMPREF0758_3534 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | 0.671 |
| ExbB_1 | exbD | HMPREF0758_0664 | HMPREF0758_1982 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | TonB system transport protein ExbD; COG: COG0848; Pfam: PF02472; InterPro: IPR003400. | 0.874 |
| ExbB_1 | fhuA | HMPREF0758_0664 | HMPREF0758_2169 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | TonB-dependent siderophore receptor; COG: COG1629; Pfam: PF07715,PF00593; InterPro: IPR010105. | 0.448 |
| ExbB_1 | lolE | HMPREF0758_0664 | HMPREF0758_4165 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | Lipoprotein releasing system, transmembrane protein LolE; COG: COG4591; Pfam: PF02687; InterPro: IPR011925. | 0.410 |
| ExbB_1 | pal | HMPREF0758_0664 | HMPREF0758_4830 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.509 |
| ExbB_1 | tonB | HMPREF0758_0664 | HMPREF0758_0666 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | TonB family domain protein. | 0.891 |
| ExbB_1 | yaeT | HMPREF0758_0664 | HMPREF0758_2339 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. | 0.440 |
| TonB | ExbB_1 | HMPREF0758_3534 | HMPREF0758_0664 | TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | 0.671 |
| TonB | exbB | HMPREF0758_3534 | HMPREF0758_1981 | TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | tonB-system energizer ExbB; COG: COG0811; Pfam: PF01618; InterPro: IPR014164. | 0.892 |
| TonB | exbD | HMPREF0758_3534 | HMPREF0758_1982 | TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | TonB system transport protein ExbD; COG: COG0848; Pfam: PF02472; InterPro: IPR003400. | 0.889 |
| TonB | fhuA | HMPREF0758_3534 | HMPREF0758_2169 | TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | TonB-dependent siderophore receptor; COG: COG1629; Pfam: PF07715,PF00593; InterPro: IPR010105. | 0.953 |
| TonB | tolB | HMPREF0758_3534 | HMPREF0758_4831 | TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.600 |
| TonB | tolQ | HMPREF0758_3534 | HMPREF0758_4834 | TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. | 0.696 |
| exbB | TonB | HMPREF0758_1981 | HMPREF0758_3534 | tonB-system energizer ExbB; COG: COG0811; Pfam: PF01618; InterPro: IPR014164. | TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | 0.892 |
| exbB | exbD | HMPREF0758_1981 | HMPREF0758_1982 | tonB-system energizer ExbB; COG: COG0811; Pfam: PF01618; InterPro: IPR014164. | TonB system transport protein ExbD; COG: COG0848; Pfam: PF02472; InterPro: IPR003400. | 0.996 |
| exbB | fhuA | HMPREF0758_1981 | HMPREF0758_2169 | tonB-system energizer ExbB; COG: COG0811; Pfam: PF01618; InterPro: IPR014164. | TonB-dependent siderophore receptor; COG: COG1629; Pfam: PF07715,PF00593; InterPro: IPR010105. | 0.681 |
| exbB | lolE | HMPREF0758_1981 | HMPREF0758_4165 | tonB-system energizer ExbB; COG: COG0811; Pfam: PF01618; InterPro: IPR014164. | Lipoprotein releasing system, transmembrane protein LolE; COG: COG4591; Pfam: PF02687; InterPro: IPR011925. | 0.657 |
| exbB | pal | HMPREF0758_1981 | HMPREF0758_4830 | tonB-system energizer ExbB; COG: COG0811; Pfam: PF01618; InterPro: IPR014164. | Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.696 |
| exbB | tolB | HMPREF0758_1981 | HMPREF0758_4831 | tonB-system energizer ExbB; COG: COG0811; Pfam: PF01618; InterPro: IPR014164. | Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.725 |
| exbB | tonB | HMPREF0758_1981 | HMPREF0758_0666 | tonB-system energizer ExbB; COG: COG0811; Pfam: PF01618; InterPro: IPR014164. | TonB family domain protein. | 0.650 |