| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CzcA | EFE96566.1 | HMPREF0758_1997 | HMPREF0758_1995 | RND transporter, HAE1/HME family, permease protein; COG: COG0841; Pfam: PF00873; InterPro: IPR001036; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Transcriptional regulator, TetR family; Pfam: PF00440; InterPro: IPR001647. | 0.881 |
| CzcA | MexA | HMPREF0758_1997 | HMPREF0758_1996 | RND transporter, HAE1/HME family, permease protein; COG: COG0841; Pfam: PF00873; InterPro: IPR001036; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.970 |
| CzcA | bpeA | HMPREF0758_1997 | HMPREF0758_0171 | RND transporter, HAE1/HME family, permease protein; COG: COG0841; Pfam: PF00873; InterPro: IPR001036; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.551 |
| CzcA | macA | HMPREF0758_1997 | HMPREF0758_4461 | RND transporter, HAE1/HME family, permease protein; COG: COG0841; Pfam: PF00873; InterPro: IPR001036; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.539 |
| CzcA | macB | HMPREF0758_1997 | HMPREF0758_4460 | RND transporter, HAE1/HME family, permease protein; COG: COG0841; Pfam: PF00873; InterPro: IPR001036; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.412 |
| CzcA | mdtA | HMPREF0758_1997 | HMPREF0758_2572 | RND transporter, HAE1/HME family, permease protein; COG: COG0841; Pfam: PF00873; InterPro: IPR001036; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; overlaps another CDS with the same product name; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.595 |
| EFE96566.1 | CzcA | HMPREF0758_1995 | HMPREF0758_1997 | Transcriptional regulator, TetR family; Pfam: PF00440; InterPro: IPR001647. | RND transporter, HAE1/HME family, permease protein; COG: COG0841; Pfam: PF00873; InterPro: IPR001036; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.881 |
| EFE96566.1 | MexA | HMPREF0758_1995 | HMPREF0758_1996 | Transcriptional regulator, TetR family; Pfam: PF00440; InterPro: IPR001647. | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.893 |
| MexA | CzcA | HMPREF0758_1996 | HMPREF0758_1997 | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | RND transporter, HAE1/HME family, permease protein; COG: COG0841; Pfam: PF00873; InterPro: IPR001036; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.970 |
| MexA | EFE96566.1 | HMPREF0758_1996 | HMPREF0758_1995 | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Transcriptional regulator, TetR family; Pfam: PF00440; InterPro: IPR001647. | 0.893 |
| MexA | macB | HMPREF0758_1996 | HMPREF0758_4460 | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.975 |
| bpeA | CzcA | HMPREF0758_0171 | HMPREF0758_1997 | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | RND transporter, HAE1/HME family, permease protein; COG: COG0841; Pfam: PF00873; InterPro: IPR001036; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.551 |
| bpeA | macB | HMPREF0758_0171 | HMPREF0758_4460 | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.980 |
| macA | CzcA | HMPREF0758_4461 | HMPREF0758_1997 | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | RND transporter, HAE1/HME family, permease protein; COG: COG0841; Pfam: PF00873; InterPro: IPR001036; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.539 |
| macA | macB | HMPREF0758_4461 | HMPREF0758_4460 | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.998 |
| macB | CzcA | HMPREF0758_4460 | HMPREF0758_1997 | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | RND transporter, HAE1/HME family, permease protein; COG: COG0841; Pfam: PF00873; InterPro: IPR001036; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.412 |
| macB | MexA | HMPREF0758_4460 | HMPREF0758_1996 | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.975 |
| macB | bpeA | HMPREF0758_4460 | HMPREF0758_0171 | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.980 |
| macB | macA | HMPREF0758_4460 | HMPREF0758_4461 | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.998 |
| macB | mdtA | HMPREF0758_4460 | HMPREF0758_2572 | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; overlaps another CDS with the same product name; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.978 |