| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adh2 | gspO | HMPREF0758_2036 | HMPREF0758_2035 | GroES-like protein; COG: COG1064; Pfam: PF08240,PF00107; InterPro: IPR002085. | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | 0.513 |
| dprA | gspO | HMPREF0758_0927 | HMPREF0758_2035 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | 0.633 |
| dprA | hofC | HMPREF0758_0927 | HMPREF0758_0498 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | Bacterial type II secretion system domain protein F; COG: COG1459; Pfam: PF00482; InterPro: IPR001992. | 0.595 |
| dprA | ispE | HMPREF0758_0927 | HMPREF0758_2117 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | Twitching motility protein; COG: COG2805; Pfam: PF00437; InterPro: IPR006321. | 0.585 |
| dprA | pilB | HMPREF0758_0927 | HMPREF0758_0497 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | Type II/IV secretion system protein; COG: COG2804; Pfam: PF00437; InterPro: IPR001482. | 0.609 |
| dprA | ppdA | HMPREF0758_0927 | HMPREF0758_2299 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | Prepilin-type cleavage/methylation N-terminal domain protein; COG: COG2165; Pfam: PF07963. | 0.479 |
| dprA | rec | HMPREF0758_0927 | HMPREF0758_4381 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.881 |
| dprA | topA | HMPREF0758_0927 | HMPREF0758_0196 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | Competence protein ComEA helix-hairpin-helix repeat region; COG: COG1555; InterPro: IPR004509. | 0.470 |
| gspO | adh2 | HMPREF0758_2035 | HMPREF0758_2036 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | GroES-like protein; COG: COG1064; Pfam: PF08240,PF00107; InterPro: IPR002085. | 0.513 |
| gspO | dprA | HMPREF0758_2035 | HMPREF0758_0927 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | 0.633 |
| gspO | hofC | HMPREF0758_2035 | HMPREF0758_0498 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Bacterial type II secretion system domain protein F; COG: COG1459; Pfam: PF00482; InterPro: IPR001992. | 0.764 |
| gspO | ispE | HMPREF0758_2035 | HMPREF0758_2117 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Twitching motility protein; COG: COG2805; Pfam: PF00437; InterPro: IPR006321. | 0.618 |
| gspO | pilB | HMPREF0758_2035 | HMPREF0758_0497 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Type II/IV secretion system protein; COG: COG2804; Pfam: PF00437; InterPro: IPR001482. | 0.708 |
| gspO | pilQ | HMPREF0758_2035 | HMPREF0758_1026 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Type IV pilus secretin PilQ; COG: COG4796; Pfam: PF07660,PF03958,PF00263; InterPro: IPR013355. | 0.664 |
| gspO | ppdA | HMPREF0758_2035 | HMPREF0758_2299 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Prepilin-type cleavage/methylation N-terminal domain protein; COG: COG2165; Pfam: PF07963. | 0.437 |
| gspO | ppdD | HMPREF0758_2035 | HMPREF0758_0496 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Prepilin-type cleavage/methylation N-terminal domain protein; COG: COG4969; Pfam: PF07963; InterPro: IPR001082; Belongs to the N-Me-Phe pilin family. | 0.464 |
| gspO | rec | HMPREF0758_2035 | HMPREF0758_4381 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.747 |
| gspO | topA | HMPREF0758_2035 | HMPREF0758_0196 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Competence protein ComEA helix-hairpin-helix repeat region; COG: COG1555; InterPro: IPR004509. | 0.601 |
| hofC | dprA | HMPREF0758_0498 | HMPREF0758_0927 | Bacterial type II secretion system domain protein F; COG: COG1459; Pfam: PF00482; InterPro: IPR001992. | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | 0.595 |
| hofC | gspO | HMPREF0758_0498 | HMPREF0758_2035 | Bacterial type II secretion system domain protein F; COG: COG1459; Pfam: PF00482; InterPro: IPR001992. | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | 0.764 |