STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (302 aa)    
Predicted Functional Partners:
speD
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
 
 
 0.999
speB
Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.
  
 
 0.957
speF
Orn/Lys/Arg decarboxylase, major domain protein; COG: COG1982; Pfam: PF03709,PF01276,PF03711; InterPro: IPR000310.
  
 
 0.917
speF2
Orn/Lys/Arg decarboxylase, major domain protein; COG: COG1982; Pfam: PF03709,PF01276,PF03711; InterPro: IPR000310; overlaps another CDS with the same product name.
  
 
 0.917
speG
Diamine N-acetyltransferase; COG: COG1670; Pfam: PF00583; InterPro: IPR016181.
    
 0.917
glnA-3
Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family.
   
 
 0.907
glnA-4
Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family.
   
 
 0.907
TriA
Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680.
   
  0.906
GuaD_1
Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680.
   
  0.906
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...]
    
 0.901
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.