| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE93285.1 | EFE95441.1 | HMPREF0758_5017 | HMPREF0758_2861 | Hypothetical protein; Pfam: PF05785; InterPro: IPR008430. | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | 0.815 |
| EFE93285.1 | hrpB | HMPREF0758_5017 | HMPREF0758_2167 | Hypothetical protein; Pfam: PF05785; InterPro: IPR008430. | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | 0.720 |
| EFE95441.1 | EFE93285.1 | HMPREF0758_2861 | HMPREF0758_5017 | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | Hypothetical protein; Pfam: PF05785; InterPro: IPR008430. | 0.815 |
| EFE95441.1 | hrpB | HMPREF0758_2861 | HMPREF0758_2167 | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | 0.920 |
| hrpB | EFE93285.1 | HMPREF0758_2167 | HMPREF0758_5017 | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | Hypothetical protein; Pfam: PF05785; InterPro: IPR008430. | 0.720 |
| hrpB | EFE95441.1 | HMPREF0758_2167 | HMPREF0758_2861 | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | 0.920 |
| hrpB | ligT | HMPREF0758_2167 | HMPREF0758_2166 | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.585 |
| hrpB | rnd | HMPREF0758_2167 | HMPREF0758_3456 | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | 0.887 |
| hrpB | rph | HMPREF0758_2167 | HMPREF0758_1271 | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.725 |
| hrpB | rpsA | HMPREF0758_2167 | HMPREF0758_4383 | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.836 |
| hrpB | rpsD | HMPREF0758_2167 | HMPREF0758_0938 | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.858 |
| hrpB | rpsE | HMPREF0758_2167 | HMPREF0758_0944 | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.751 |
| hrpB | rpsK | HMPREF0758_2167 | HMPREF0758_0939 | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.781 |
| hrpB | sfsA | HMPREF0758_2167 | HMPREF0758_2165 | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | Sugar fermentation stimulation protein; COG: COG1489; Pfam: PF03749; InterPro: IPR005224; Belongs to the SfsA family. | 0.581 |
| ligT | hrpB | HMPREF0758_2166 | HMPREF0758_2167 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | 0.585 |
| ligT | sfsA | HMPREF0758_2166 | HMPREF0758_2165 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Sugar fermentation stimulation protein; COG: COG1489; Pfam: PF03749; InterPro: IPR005224; Belongs to the SfsA family. | 0.816 |
| rnd | hrpB | HMPREF0758_3456 | HMPREF0758_2167 | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | ATP-dependent helicase HrpB; COG: COG1643; Pfam: PF00270,PF00271,PF04408,PF08482; InterPro: IPR010225. | 0.887 |
| rnd | rph | HMPREF0758_3456 | HMPREF0758_1271 | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.978 |
| rnd | rpsA | HMPREF0758_3456 | HMPREF0758_4383 | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.951 |
| rnd | rpsD | HMPREF0758_3456 | HMPREF0758_0938 | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.909 |