STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (384 aa)    
Predicted Functional Partners:
yxjG
Methionine synthase, vitamin-B12 independent; COG: COG0620; Pfam: PF01717.
  
 0.959
XecA1
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase family protein; COG: COG0620; Pfam: PF01717; InterPro: IPR002629; overlaps another CDS with the same product name.
  
 0.959
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 0.959
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.952
speD
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
    
 0.939
mmuM
Homocysteine S-methyltransferase; COG: COG2040; Pfam: PF02574; InterPro: IPR003726.
     
 0.934
dcm
DNA (cytosine-5-)-methyltransferase; COG: COG0270; Pfam: PF00145; InterPro: IPR001525; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.919
dcm-2
DNA (cytosine-5-)-methyltransferase; COG: COG0270; Pfam: PF00145; InterPro: IPR001525; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.919
tyrB
Aminotransferase, class I/II; COG: COG1448; Pfam: PF00155; InterPro: IPR000796.
     
 0.908
lasI
Acyl-homoserine-lactone synthase; COG: COG3916; Pfam: PF00765; InterPro: IPR016181.
     
 0.900
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.