STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpaE2Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. (489 aa)    
Predicted Functional Partners:
betA
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
  
 
 0.910
betB-2
Betaine-aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.
  
  
 
0.910
ilvB3
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein; Pfam: PF02776,PF00205,PF02775; InterPro: IPR012001; Belongs to the TPP enzyme family.
 
 
 0.781
EFE96254.1
Cupin domain protein; Pfam: PF07883; InterPro: IPR013096.
    0.765
oxrA
Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040.
 
   0.749
nadX
Hypothetical protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
 
    0.743
acoC
Hydrolase, alpha/beta domain protein; Pfam: PF00561; InterPro: IPR000073.
  
    0.671
GudP_2
Transporter, major facilitator family protein; Pfam: PF07690; InterPro: IPR011701.
      0.621
nifJ
Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895.
  
 
 0.544
DbfB
Glyoxalase family protein; Pfam: PF00903; InterPro: IPR004360.
 
   
 0.533
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.