| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PfkA_2 | eno | HMPREF0758_3845 | HMPREF0758_0472 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.746 |
| PfkA_2 | fbaA | HMPREF0758_3845 | HMPREF0758_2200 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.938 |
| PfkA_2 | fbp | HMPREF0758_3845 | HMPREF0758_0830 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | Fructose-1,6-bisphosphatase; COG: COG0158; Pfam: PF00316; InterPro: IPR000146; Belongs to the FBPase class 1 family. | 0.921 |
| PfkA_2 | fruA | HMPREF0758_3845 | HMPREF0758_2890 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF02379,PF02378; InterPro: IPR006327. | 0.485 |
| PfkA_2 | gap | HMPREF0758_3845 | HMPREF0758_3492 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.576 |
| PfkA_2 | pfkA | HMPREF0758_3845 | HMPREF0758_1183 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.925 |
| PfkA_2 | pfkB | HMPREF0758_3845 | HMPREF0758_2889 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | 1-phosphofructokinase; COG: COG1105; Pfam: PF00294; InterPro: IPR011611; Belongs to the carbohydrate kinase PfkB family. | 0.929 |
| PfkA_2 | tal | HMPREF0758_3845 | HMPREF0758_0585 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.911 |
| PfkA_2 | tal-2 | HMPREF0758_3845 | HMPREF0758_2628 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.911 |
| PfkA_2 | tpiA | HMPREF0758_3845 | HMPREF0758_1181 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.775 |
| eno | PfkA_2 | HMPREF0758_0472 | HMPREF0758_3845 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | 0.746 |
| eno | fbaA | HMPREF0758_0472 | HMPREF0758_2200 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.940 |
| eno | fbp | HMPREF0758_0472 | HMPREF0758_0830 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Fructose-1,6-bisphosphatase; COG: COG0158; Pfam: PF00316; InterPro: IPR000146; Belongs to the FBPase class 1 family. | 0.560 |
| eno | fruA | HMPREF0758_0472 | HMPREF0758_2890 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF02379,PF02378; InterPro: IPR006327. | 0.408 |
| eno | gap | HMPREF0758_0472 | HMPREF0758_3492 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.906 |
| eno | pfkA | HMPREF0758_0472 | HMPREF0758_1183 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.783 |
| eno | tal | HMPREF0758_0472 | HMPREF0758_0585 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.883 |
| eno | tal-2 | HMPREF0758_0472 | HMPREF0758_2628 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.883 |
| eno | tpiA | HMPREF0758_0472 | HMPREF0758_1181 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.982 |
| fbaA | PfkA_2 | HMPREF0758_2200 | HMPREF0758_3845 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. | 0.938 |