| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94373.1 | aad | HMPREF0758_3947 | HMPREF0758_3517 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913; InterPro: IPR004113. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.570 |
| EFE94373.1 | glpC | HMPREF0758_3947 | HMPREF0758_1558 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913; InterPro: IPR004113. | Glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; COG: COG0247; Pfam: PF02754; InterPro: IPR012285. | 0.558 |
| EFE94373.1 | lctP | HMPREF0758_3947 | HMPREF0758_2266 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913; InterPro: IPR004113. | Transporter, lactate permease (LctP) family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | 0.769 |
| EFE94373.1 | lldD | HMPREF0758_3947 | HMPREF0758_2265 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913; InterPro: IPR004113. | Dehydrogenase, FMN-dependent; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. | 0.861 |
| EFE94373.1 | mdh | HMPREF0758_3947 | HMPREF0758_0824 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913; InterPro: IPR004113. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.415 |
| EFE94373.1 | nifJ | HMPREF0758_3947 | HMPREF0758_3621 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913; InterPro: IPR004113. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.744 |
| EFE94373.1 | pta | HMPREF0758_3947 | HMPREF0758_2779 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913; InterPro: IPR004113. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.564 |
| aad | EFE94373.1 | HMPREF0758_3517 | HMPREF0758_3947 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913; InterPro: IPR004113. | 0.570 |
| aad | lctP | HMPREF0758_3517 | HMPREF0758_2266 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Transporter, lactate permease (LctP) family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | 0.472 |
| aad | lldD | HMPREF0758_3517 | HMPREF0758_2265 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Dehydrogenase, FMN-dependent; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. | 0.465 |
| aad | mdh | HMPREF0758_3517 | HMPREF0758_0824 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.492 |
| aad | nifJ | HMPREF0758_3517 | HMPREF0758_3621 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.972 |
| aad | pta | HMPREF0758_3517 | HMPREF0758_2779 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.950 |
| aad | putA | HMPREF0758_3517 | HMPREF0758_3240 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.558 |
| dld | lctP | HMPREF0758_4757 | HMPREF0758_2266 | FAD binding domain protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | Transporter, lactate permease (LctP) family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | 0.456 |
| dld | lldD | HMPREF0758_4757 | HMPREF0758_2265 | FAD binding domain protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | Dehydrogenase, FMN-dependent; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. | 0.957 |
| dld | nifJ | HMPREF0758_4757 | HMPREF0758_3621 | FAD binding domain protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.955 |
| dld | pta | HMPREF0758_4757 | HMPREF0758_2779 | FAD binding domain protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.438 |
| glpC | EFE94373.1 | HMPREF0758_1558 | HMPREF0758_3947 | Glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; COG: COG0247; Pfam: PF02754; InterPro: IPR012285. | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913; InterPro: IPR004113. | 0.558 |
| glpC | lctP | HMPREF0758_1558 | HMPREF0758_2266 | Glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; COG: COG0247; Pfam: PF02754; InterPro: IPR012285. | Transporter, lactate permease (LctP) family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | 0.589 |