STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysADiaminopimelate decarboxylase; COG: COG0019; Pfam: PF02784,PF00278; InterPro: IPR002986. (354 aa)    
Predicted Functional Partners:
lysC
Aspartate kinase, monofunctional class; COG: COG0527; Pfam: PF00696,PF01842; InterPro: IPR005260; Belongs to the aspartokinase family.
   
 0.949
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 0.824
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
 0.801
dapA-2
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 0.713
thrA
Homoserine dehydrogenase; COG: COG0527; Pfam: PF00696,PF01842,PF03447,PF00742; InterPro: IPR001341; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 0.700
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
  
 0.680
lysR4
LysR substrate binding domain protein; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family.
 
     0.676
yiiD
Putative thioesterase domain protein; Pfam: PF00583; InterPro: IPR016181.
  
  
 0.636
argA
Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily.
 
  
 0.636
hisE
phosphoribosyl-ATP diphosphatase; COG: COG0139; Pfam: PF01502,PF01503; InterPro: IPR008179; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.592
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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