STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcvAGlycine cleavage system transcriptional activator; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. (305 aa)    
Predicted Functional Partners:
YgdD
Hypothetical protein; COG: COG2363; Pfam: PF04241; InterPro: IPR006696.
  
    0.698
YejL
Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family.
  
     0.667
fadR
Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism.
  
  
 0.651
seqA
SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
     0.617
rlmM
Putative ribosomal RNA large subunit methyltransferase M; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
  
    0.616
YofA_2
LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family.
  
     0.594
CysL_1
LysR substrate binding domain protein; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family.
  
     0.590
EFE95529.1
YfcL protein; Pfam: PF08891; InterPro: IPR014987.
  
     0.577
oxyR
LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family.
  
     0.502
gcvR
Glycine cleavage system transcriptional repressor; COG: COG2716; Pfam: PF01842.
  
 
 
 0.447
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
Server load: low (34%) [HD]