| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CysL_1 | gcvA | HMPREF0758_2975 | HMPREF0758_2314 | LysR substrate binding domain protein; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | Glycine cleavage system transcriptional activator; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | 0.590 |
| EFE95529.1 | YejL | HMPREF0758_2731 | HMPREF0758_2857 | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | 0.766 |
| EFE95529.1 | fadR | HMPREF0758_2731 | HMPREF0758_3469 | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | 0.720 |
| EFE95529.1 | gcvA | HMPREF0758_2731 | HMPREF0758_2314 | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | Glycine cleavage system transcriptional activator; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | 0.577 |
| EFE95529.1 | gcvR | HMPREF0758_2731 | HMPREF0758_2600 | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | Glycine cleavage system transcriptional repressor; COG: COG2716; Pfam: PF01842. | 0.497 |
| EFE95529.1 | seqA | HMPREF0758_2731 | HMPREF0758_4875 | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.768 |
| YejL | EFE95529.1 | HMPREF0758_2857 | HMPREF0758_2731 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | 0.766 |
| YejL | fadR | HMPREF0758_2857 | HMPREF0758_3469 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | 0.772 |
| YejL | gcvA | HMPREF0758_2857 | HMPREF0758_2314 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Glycine cleavage system transcriptional activator; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | 0.667 |
| YejL | gcvR | HMPREF0758_2857 | HMPREF0758_2600 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Glycine cleavage system transcriptional repressor; COG: COG2716; Pfam: PF01842. | 0.452 |
| YejL | seqA | HMPREF0758_2857 | HMPREF0758_4875 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.774 |
| YgdD | gcvA | HMPREF0758_2315 | HMPREF0758_2314 | Hypothetical protein; COG: COG2363; Pfam: PF04241; InterPro: IPR006696. | Glycine cleavage system transcriptional activator; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | 0.698 |
| YgdD | rlmM | HMPREF0758_2315 | HMPREF0758_2316 | Hypothetical protein; COG: COG2363; Pfam: PF04241; InterPro: IPR006696. | Putative ribosomal RNA large subunit methyltransferase M; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.907 |
| YofA_2 | gcvA | HMPREF0758_4709 | HMPREF0758_2314 | LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | Glycine cleavage system transcriptional activator; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | 0.594 |
| fadR | EFE95529.1 | HMPREF0758_3469 | HMPREF0758_2731 | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | 0.720 |
| fadR | YejL | HMPREF0758_3469 | HMPREF0758_2857 | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | 0.772 |
| fadR | gcvA | HMPREF0758_3469 | HMPREF0758_2314 | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | Glycine cleavage system transcriptional activator; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | 0.651 |
| fadR | seqA | HMPREF0758_3469 | HMPREF0758_4875 | Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.765 |
| gcvA | CysL_1 | HMPREF0758_2314 | HMPREF0758_2975 | Glycine cleavage system transcriptional activator; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | LysR substrate binding domain protein; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | 0.590 |
| gcvA | EFE95529.1 | HMPREF0758_2314 | HMPREF0758_2731 | Glycine cleavage system transcriptional activator; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | 0.577 |