| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE96700.1 | YejL | HMPREF0758_1675 | HMPREF0758_2857 | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | 0.558 |
| EFE96700.1 | YfbV | HMPREF0758_1675 | HMPREF0758_2781 | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | 0.507 |
| EFE96700.1 | lptC | HMPREF0758_1675 | HMPREF0758_1854 | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.704 |
| EFE96700.1 | proQ | HMPREF0758_1675 | HMPREF0758_4013 | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | ProQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.740 |
| EFE96700.1 | rraB | HMPREF0758_1675 | HMPREF0758_0750 | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.686 |
| EFE96700.1 | seqA | HMPREF0758_1675 | HMPREF0758_4875 | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.697 |
| EFE96700.1 | syd | HMPREF0758_1675 | HMPREF0758_2320 | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | Syd protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.732 |
| EFE96700.1 | yihI | HMPREF0758_1675 | HMPREF0758_1301 | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | Hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.543 |
| EFE96700.1 | zapC | HMPREF0758_1675 | HMPREF0758_4351 | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | Hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. | 0.562 |
| YejL | EFE96700.1 | HMPREF0758_2857 | HMPREF0758_1675 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | 0.558 |
| YejL | YfbV | HMPREF0758_2857 | HMPREF0758_2781 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | 0.769 |
| YejL | dedD | HMPREF0758_2857 | HMPREF0758_2760 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Sporulation and cell division repeat protein; Non-essential cell division protein that could be required for efficient cell constriction. | 0.715 |
| YejL | lptC | HMPREF0758_2857 | HMPREF0758_1854 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.729 |
| YejL | proQ | HMPREF0758_2857 | HMPREF0758_4013 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | ProQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.745 |
| YejL | rraB | HMPREF0758_2857 | HMPREF0758_0750 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.760 |
| YejL | seqA | HMPREF0758_2857 | HMPREF0758_4875 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.774 |
| YejL | syd | HMPREF0758_2857 | HMPREF0758_2320 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Syd protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.698 |
| YejL | yihI | HMPREF0758_2857 | HMPREF0758_1301 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.762 |
| YejL | zapC | HMPREF0758_2857 | HMPREF0758_4351 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. | 0.709 |
| YfbV | EFE96700.1 | HMPREF0758_2781 | HMPREF0758_1675 | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | 0.507 |