| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| frr | pyrH | HMPREF0758_2333 | HMPREF0758_2332 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.976 |
| frr | rplA | HMPREF0758_2333 | HMPREF0758_1659 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.958 |
| frr | rplS | HMPREF0758_2333 | HMPREF0758_0411 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.976 |
| frr | rplT | HMPREF0758_2333 | HMPREF0758_3981 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.987 |
| frr | rpsB | HMPREF0758_2333 | HMPREF0758_2329 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Ribosomal protein S2; COG: COG0052; Pfam: PF00318; InterPro: IPR005706; Belongs to the universal ribosomal protein uS2 family. | 0.989 |
| frr | tig | HMPREF0758_2333 | HMPREF0758_0202 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.874 |
| frr | tsf | HMPREF0758_2333 | HMPREF0758_2331 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.922 |
| frr | tsf-2 | HMPREF0758_2333 | HMPREF0758_2330 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | UBA/TS-N domain protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.897 |
| pyrH | frr | HMPREF0758_2332 | HMPREF0758_2333 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.976 |
| pyrH | rplA | HMPREF0758_2332 | HMPREF0758_1659 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.860 |
| pyrH | rplS | HMPREF0758_2332 | HMPREF0758_0411 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.620 |
| pyrH | rpsB | HMPREF0758_2332 | HMPREF0758_2329 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Ribosomal protein S2; COG: COG0052; Pfam: PF00318; InterPro: IPR005706; Belongs to the universal ribosomal protein uS2 family. | 0.961 |
| pyrH | tig | HMPREF0758_2332 | HMPREF0758_0202 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.727 |
| pyrH | tsf | HMPREF0758_2332 | HMPREF0758_2331 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.921 |
| pyrH | tsf-2 | HMPREF0758_2332 | HMPREF0758_2330 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | UBA/TS-N domain protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.921 |
| rplA | frr | HMPREF0758_1659 | HMPREF0758_2333 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.958 |
| rplA | pyrH | HMPREF0758_1659 | HMPREF0758_2332 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.860 |
| rplA | rplS | HMPREF0758_1659 | HMPREF0758_0411 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.996 |
| rplA | rplT | HMPREF0758_1659 | HMPREF0758_3981 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.994 |
| rplA | rpsB | HMPREF0758_1659 | HMPREF0758_2329 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosomal protein S2; COG: COG0052; Pfam: PF00318; InterPro: IPR005706; Belongs to the universal ribosomal protein uS2 family. | 0.996 |