node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
YaeB | metQ | HMPREF0758_2364 | HMPREF0758_2366 | Methyltransferase, YaeB family; COG: COG1720; Pfam: PF01980; InterPro: IPR001378. | D-methionine-binding lipoprotein MetQ; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | 0.441 |
YaeB | proS | HMPREF0758_2364 | HMPREF0758_2363 | Methyltransferase, YaeB family; COG: COG1720; Pfam: PF01980; InterPro: IPR001378. | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.549 |
YaeB | rcsF | HMPREF0758_2364 | HMPREF0758_2365 | Methyltransferase, YaeB family; COG: COG1720; Pfam: PF01980; InterPro: IPR001378. | Outer membrane lipoprotein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. | 0.794 |
YaeB | tmcA | HMPREF0758_2364 | HMPREF0758_2605 | Methyltransferase, YaeB family; COG: COG1720; Pfam: PF01980; InterPro: IPR001378. | Acetyltransferase, GNAT family; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.454 |
metQ | YaeB | HMPREF0758_2366 | HMPREF0758_2364 | D-methionine-binding lipoprotein MetQ; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | Methyltransferase, YaeB family; COG: COG1720; Pfam: PF01980; InterPro: IPR001378. | 0.441 |
metQ | rcsF | HMPREF0758_2366 | HMPREF0758_2365 | D-methionine-binding lipoprotein MetQ; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | Outer membrane lipoprotein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. | 0.438 |
proS | YaeB | HMPREF0758_2363 | HMPREF0758_2364 | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | Methyltransferase, YaeB family; COG: COG1720; Pfam: PF01980; InterPro: IPR001378. | 0.549 |
proS | rcsF | HMPREF0758_2363 | HMPREF0758_2365 | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | Outer membrane lipoprotein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. | 0.542 |
rcsF | YaeB | HMPREF0758_2365 | HMPREF0758_2364 | Outer membrane lipoprotein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. | Methyltransferase, YaeB family; COG: COG1720; Pfam: PF01980; InterPro: IPR001378. | 0.794 |
rcsF | metQ | HMPREF0758_2365 | HMPREF0758_2366 | Outer membrane lipoprotein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. | D-methionine-binding lipoprotein MetQ; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | 0.438 |
rcsF | proS | HMPREF0758_2365 | HMPREF0758_2363 | Outer membrane lipoprotein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.542 |
tmcA | YaeB | HMPREF0758_2605 | HMPREF0758_2364 | Acetyltransferase, GNAT family; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | Methyltransferase, YaeB family; COG: COG1720; Pfam: PF01980; InterPro: IPR001378. | 0.454 |