| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| actP | gor | HMPREF0758_0141 | HMPREF0758_1103 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | Glutathione-disulfide reductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006322. | 0.495 |
| actP | nifJ | HMPREF0758_0141 | HMPREF0758_3621 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.599 |
| actP | trxA-2 | HMPREF0758_0141 | HMPREF0758_2376 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | Thioredoxin; COG: COG0526; Pfam: PF00085; InterPro: IPR012335; Belongs to the thioredoxin family. | 0.510 |
| actP | trxB | HMPREF0758_0141 | HMPREF0758_4452 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | Thioredoxin-disulfide reductase; COG: COG0492; Pfam: PF07992,PF00070; InterPro: IPR005982. | 0.496 |
| actP | wzb | HMPREF0758_0141 | HMPREF0758_4569 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | Low molecular weight phosphotyrosine protein phosphatase; COG: COG0394; Pfam: PF01451; InterPro: IPR000106; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.490 |
| gor | actP | HMPREF0758_1103 | HMPREF0758_0141 | Glutathione-disulfide reductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006322. | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | 0.495 |
| gor | nifJ | HMPREF0758_1103 | HMPREF0758_3621 | Glutathione-disulfide reductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006322. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.551 |
| gor | trxA-2 | HMPREF0758_1103 | HMPREF0758_2376 | Glutathione-disulfide reductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006322. | Thioredoxin; COG: COG0526; Pfam: PF00085; InterPro: IPR012335; Belongs to the thioredoxin family. | 0.458 |
| gor | trxB | HMPREF0758_1103 | HMPREF0758_4452 | Glutathione-disulfide reductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006322. | Thioredoxin-disulfide reductase; COG: COG0492; Pfam: PF07992,PF00070; InterPro: IPR005982. | 0.512 |
| grpE | nifJ | HMPREF0758_2441 | HMPREF0758_3621 | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.587 |
| grpE | trxA-2 | HMPREF0758_2441 | HMPREF0758_2376 | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Thioredoxin; COG: COG0526; Pfam: PF00085; InterPro: IPR012335; Belongs to the thioredoxin family. | 0.498 |
| grpE | trxB | HMPREF0758_2441 | HMPREF0758_4452 | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Thioredoxin-disulfide reductase; COG: COG0492; Pfam: PF07992,PF00070; InterPro: IPR005982. | 0.415 |
| nifJ | actP | HMPREF0758_3621 | HMPREF0758_0141 | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | 0.599 |
| nifJ | gor | HMPREF0758_3621 | HMPREF0758_1103 | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | Glutathione-disulfide reductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006322. | 0.551 |
| nifJ | grpE | HMPREF0758_3621 | HMPREF0758_2441 | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.587 |
| nifJ | putA | HMPREF0758_3621 | HMPREF0758_3240 | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.626 |
| nifJ | trxA-2 | HMPREF0758_3621 | HMPREF0758_2376 | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | Thioredoxin; COG: COG0526; Pfam: PF00085; InterPro: IPR012335; Belongs to the thioredoxin family. | 0.448 |
| nifJ | trxB | HMPREF0758_3621 | HMPREF0758_4452 | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | Thioredoxin-disulfide reductase; COG: COG0492; Pfam: PF07992,PF00070; InterPro: IPR005982. | 0.606 |
| nifJ | yfiQ | HMPREF0758_3621 | HMPREF0758_2374 | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | CoA binding domain protein; COG: COG1042; Pfam: PF02629,PF00583; InterPro: IPR016102. | 0.737 |
| putA | nifJ | HMPREF0758_3240 | HMPREF0758_3621 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.626 |