| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE96085.1 | nrdA | HMPREF0758_2350 | HMPREF0758_2829 | Hypothetical protein. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.625 |
| EFE96085.1 | nrdE | HMPREF0758_2350 | HMPREF0758_2398 | Hypothetical protein. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.625 |
| EFE96085.1 | nrdI | HMPREF0758_2350 | HMPREF0758_2399 | Hypothetical protein. | nrdI protein; Probably involved in ribonucleotide reductase function. | 0.583 |
| ahp | entF | HMPREF0758_1150 | HMPREF0758_2676 | Glutaredoxin-family domain protein; COG: COG0678; Pfam: PF08534,PF00462; InterPro: IPR012335. | AMP-binding enzyme; COG: COG1020; Pfam: PF00668,PF00501,PF00550,PF00975; InterPro: IPR010071. | 0.408 |
| ahp | nrdA | HMPREF0758_1150 | HMPREF0758_2829 | Glutaredoxin-family domain protein; COG: COG0678; Pfam: PF08534,PF00462; InterPro: IPR012335. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.685 |
| ahp | nrdE | HMPREF0758_1150 | HMPREF0758_2398 | Glutaredoxin-family domain protein; COG: COG0678; Pfam: PF08534,PF00462; InterPro: IPR012335. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.634 |
| ahp | nrdI | HMPREF0758_1150 | HMPREF0758_2399 | Glutaredoxin-family domain protein; COG: COG0678; Pfam: PF08534,PF00462; InterPro: IPR012335. | nrdI protein; Probably involved in ribonucleotide reductase function. | 0.583 |
| entF | ahp | HMPREF0758_2676 | HMPREF0758_1150 | AMP-binding enzyme; COG: COG1020; Pfam: PF00668,PF00501,PF00550,PF00975; InterPro: IPR010071. | Glutaredoxin-family domain protein; COG: COG0678; Pfam: PF08534,PF00462; InterPro: IPR012335. | 0.408 |
| entF | nrdI | HMPREF0758_2676 | HMPREF0758_2399 | AMP-binding enzyme; COG: COG1020; Pfam: PF00668,PF00501,PF00550,PF00975; InterPro: IPR010071. | nrdI protein; Probably involved in ribonucleotide reductase function. | 0.518 |
| grxA | nrdA | HMPREF0758_4494 | HMPREF0758_2829 | Glutaredoxin, GrxA family; COG: COG0695; Pfam: PF00462; InterPro: IPR011902. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.709 |
| grxA | nrdE | HMPREF0758_4494 | HMPREF0758_2398 | Glutaredoxin, GrxA family; COG: COG0695; Pfam: PF00462; InterPro: IPR011902. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.709 |
| grxA | nrdI | HMPREF0758_4494 | HMPREF0758_2399 | Glutaredoxin, GrxA family; COG: COG0695; Pfam: PF00462; InterPro: IPR011902. | nrdI protein; Probably involved in ribonucleotide reductase function. | 0.583 |
| grxC | nrdA | HMPREF0758_1238 | HMPREF0758_2829 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.634 |
| grxC | nrdE | HMPREF0758_1238 | HMPREF0758_2398 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.634 |
| grxC | nrdI | HMPREF0758_1238 | HMPREF0758_2399 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | nrdI protein; Probably involved in ribonucleotide reductase function. | 0.583 |
| nrdA | EFE96085.1 | HMPREF0758_2829 | HMPREF0758_2350 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein. | 0.625 |
| nrdA | ahp | HMPREF0758_2829 | HMPREF0758_1150 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Glutaredoxin-family domain protein; COG: COG0678; Pfam: PF08534,PF00462; InterPro: IPR012335. | 0.685 |
| nrdA | grxA | HMPREF0758_2829 | HMPREF0758_4494 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Glutaredoxin, GrxA family; COG: COG0695; Pfam: PF00462; InterPro: IPR011902. | 0.709 |
| nrdA | grxC | HMPREF0758_2829 | HMPREF0758_1238 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.634 |
| nrdA | nrdB | HMPREF0758_2829 | HMPREF0758_2828 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase, beta subunit; COG: COG0208; Pfam: PF00268; InterPro: IPR012348. | 0.998 |