| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE95984.1 | EFE95986.1 | HMPREF0758_2422 | HMPREF0758_2424 | Hypothetical protein; Pfam: PF04657; InterPro: IPR006750. | Hypothetical protein. | 0.402 |
| EFE95984.1 | GuaD_1 | HMPREF0758_2422 | HMPREF0758_2423 | Hypothetical protein; Pfam: PF04657; InterPro: IPR006750. | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | 0.747 |
| EFE95986.1 | EFE95984.1 | HMPREF0758_2424 | HMPREF0758_2422 | Hypothetical protein. | Hypothetical protein; Pfam: PF04657; InterPro: IPR006750. | 0.402 |
| EFE95986.1 | GuaD_1 | HMPREF0758_2424 | HMPREF0758_2423 | Hypothetical protein. | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | 0.907 |
| GuaD_1 | EFE95984.1 | HMPREF0758_2423 | HMPREF0758_2422 | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | Hypothetical protein; Pfam: PF04657; InterPro: IPR006750. | 0.747 |
| GuaD_1 | EFE95986.1 | HMPREF0758_2423 | HMPREF0758_2424 | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | Hypothetical protein. | 0.907 |
| GuaD_1 | TriA | HMPREF0758_2423 | HMPREF0758_2044 | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | 0.900 |
| GuaD_1 | expI | HMPREF0758_2423 | HMPREF0758_1126 | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | Autoinducer synthetase; Pfam: PF00765; InterPro: IPR016181. | 0.900 |
| GuaD_1 | lasI | HMPREF0758_2423 | HMPREF0758_1109 | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | Acyl-homoserine-lactone synthase; COG: COG3916; Pfam: PF00765; InterPro: IPR016181. | 0.900 |
| GuaD_1 | mtnN | HMPREF0758_2423 | HMPREF0758_0488 | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] | 0.901 |
| GuaD_1 | speE | HMPREF0758_2423 | HMPREF0758_2148 | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.906 |
| TriA | GuaD_1 | HMPREF0758_2044 | HMPREF0758_2423 | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | 0.900 |
| TriA | expI | HMPREF0758_2044 | HMPREF0758_1126 | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | Autoinducer synthetase; Pfam: PF00765; InterPro: IPR016181. | 0.900 |
| TriA | lasI | HMPREF0758_2044 | HMPREF0758_1109 | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | Acyl-homoserine-lactone synthase; COG: COG3916; Pfam: PF00765; InterPro: IPR016181. | 0.900 |
| TriA | mtnN | HMPREF0758_2044 | HMPREF0758_0488 | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] | 0.901 |
| TriA | speE | HMPREF0758_2044 | HMPREF0758_2148 | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.906 |
| expI | GuaD_1 | HMPREF0758_1126 | HMPREF0758_2423 | Autoinducer synthetase; Pfam: PF00765; InterPro: IPR016181. | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | 0.900 |
| expI | TriA | HMPREF0758_1126 | HMPREF0758_2044 | Autoinducer synthetase; Pfam: PF00765; InterPro: IPR016181. | Amidohydrolase family protein; COG: COG0402; Pfam: PF01979; InterPro: IPR006680. | 0.900 |
| expI | lasI | HMPREF0758_1126 | HMPREF0758_1109 | Autoinducer synthetase; Pfam: PF00765; InterPro: IPR016181. | Acyl-homoserine-lactone synthase; COG: COG3916; Pfam: PF00765; InterPro: IPR016181. | 0.947 |
| expI | mtnN | HMPREF0758_1126 | HMPREF0758_0488 | Autoinducer synthetase; Pfam: PF00765; InterPro: IPR016181. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] | 0.903 |