| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aad | grcA | HMPREF0758_3517 | HMPREF0758_2443 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | 0.698 |
| aad | nrdD | HMPREF0758_3517 | HMPREF0758_0763 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Anaerobic ribonucleoside-triphosphate reductase; COG: COG1328; Pfam: PF03477,PF01228; InterPro: IPR012833. | 0.526 |
| aad | nrdG-2 | HMPREF0758_3517 | HMPREF0758_0764 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.511 |
| aad | pflA | HMPREF0758_3517 | HMPREF0758_3004 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Glycyl-radical enzyme activating protein family protein; COG: COG1180; Pfam: PF04055; InterPro: IPR012839. | 0.817 |
| aad | pflA-2 | HMPREF0758_3517 | HMPREF0758_4439 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.876 |
| aad | pflC | HMPREF0758_3517 | HMPREF0758_1623 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Radical SAM domain protein; COG: COG1180; Pfam: PF04055. | 0.848 |
| aad | pflD | HMPREF0758_3517 | HMPREF0758_1624 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR010098. | 0.965 |
| aad | pflD2 | HMPREF0758_3517 | HMPREF0758_3003 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR010098. | 0.962 |
| grcA | aad | HMPREF0758_2443 | HMPREF0758_3517 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.698 |
| grcA | nrdD | HMPREF0758_2443 | HMPREF0758_0763 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Anaerobic ribonucleoside-triphosphate reductase; COG: COG1328; Pfam: PF03477,PF01228; InterPro: IPR012833. | 0.409 |
| grcA | nrdG-2 | HMPREF0758_2443 | HMPREF0758_0764 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.499 |
| grcA | pflA | HMPREF0758_2443 | HMPREF0758_3004 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Glycyl-radical enzyme activating protein family protein; COG: COG1180; Pfam: PF04055; InterPro: IPR012839. | 0.772 |
| grcA | pflA-2 | HMPREF0758_2443 | HMPREF0758_4439 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.781 |
| grcA | pflC | HMPREF0758_2443 | HMPREF0758_1623 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Radical SAM domain protein; COG: COG1180; Pfam: PF04055. | 0.774 |
| grcA | pflD | HMPREF0758_2443 | HMPREF0758_1624 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR010098. | 0.420 |
| grcA | pflD2 | HMPREF0758_2443 | HMPREF0758_3003 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR010098. | 0.403 |
| grcA | ung | HMPREF0758_2443 | HMPREF0758_2442 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.526 |
| nrdD | aad | HMPREF0758_0763 | HMPREF0758_3517 | Anaerobic ribonucleoside-triphosphate reductase; COG: COG1328; Pfam: PF03477,PF01228; InterPro: IPR012833. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.526 |
| nrdD | grcA | HMPREF0758_0763 | HMPREF0758_2443 | Anaerobic ribonucleoside-triphosphate reductase; COG: COG1328; Pfam: PF03477,PF01228; InterPro: IPR012833. | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | 0.409 |
| nrdD | nrdG-2 | HMPREF0758_0763 | HMPREF0758_0764 | Anaerobic ribonucleoside-triphosphate reductase; COG: COG1328; Pfam: PF03477,PF01228; InterPro: IPR012833. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.984 |