| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IucD | purN | HMPREF0758_0364 | HMPREF0758_2590 | Hypothetical protein; COG: COG3486; 1.14.13.59. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.428 |
| IucD | speG | HMPREF0758_0364 | HMPREF0758_2589 | Hypothetical protein; COG: COG3486; 1.14.13.59. | Diamine N-acetyltransferase; COG: COG1670; Pfam: PF00583; InterPro: IPR016181. | 0.420 |
| YnfB | speG | HMPREF0758_3822 | HMPREF0758_2589 | Tat pathway signal sequence domain protein; Pfam: PF06932; InterPro: IPR009700; Belongs to the UPF0482 family. | Diamine N-acetyltransferase; COG: COG1670; Pfam: PF00583; InterPro: IPR016181. | 0.889 |
| glnA-3 | glnA-4 | HMPREF0758_2903 | HMPREF0758_4042 | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | 0.900 |
| glnA-3 | speB | HMPREF0758_2903 | HMPREF0758_2177 | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily. | 0.944 |
| glnA-3 | speE | HMPREF0758_2903 | HMPREF0758_2148 | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.907 |
| glnA-3 | speF | HMPREF0758_2903 | HMPREF0758_0780 | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | Orn/Lys/Arg decarboxylase, major domain protein; COG: COG1982; Pfam: PF03709,PF01276,PF03711; InterPro: IPR000310. | 0.900 |
| glnA-3 | speF2 | HMPREF0758_2903 | HMPREF0758_2102 | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | Orn/Lys/Arg decarboxylase, major domain protein; COG: COG1982; Pfam: PF03709,PF01276,PF03711; InterPro: IPR000310; overlaps another CDS with the same product name. | 0.900 |
| glnA-3 | speG | HMPREF0758_2903 | HMPREF0758_2589 | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | Diamine N-acetyltransferase; COG: COG1670; Pfam: PF00583; InterPro: IPR016181. | 0.903 |
| glnA-4 | glnA-3 | HMPREF0758_4042 | HMPREF0758_2903 | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | 0.900 |
| glnA-4 | speB | HMPREF0758_4042 | HMPREF0758_2177 | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily. | 0.944 |
| glnA-4 | speE | HMPREF0758_4042 | HMPREF0758_2148 | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.907 |
| glnA-4 | speF | HMPREF0758_4042 | HMPREF0758_0780 | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | Orn/Lys/Arg decarboxylase, major domain protein; COG: COG1982; Pfam: PF03709,PF01276,PF03711; InterPro: IPR000310. | 0.900 |
| glnA-4 | speF2 | HMPREF0758_4042 | HMPREF0758_2102 | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | Orn/Lys/Arg decarboxylase, major domain protein; COG: COG1982; Pfam: PF03709,PF01276,PF03711; InterPro: IPR000310; overlaps another CDS with the same product name. | 0.900 |
| glnA-4 | speG | HMPREF0758_4042 | HMPREF0758_2589 | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | Diamine N-acetyltransferase; COG: COG1670; Pfam: PF00583; InterPro: IPR016181. | 0.903 |
| purM | purN | HMPREF0758_2591 | HMPREF0758_2590 | Phosphoribosylformylglycinamidine cyclo-ligase; COG: COG0150; Pfam: PF00586,PF02769; InterPro: IPR004733. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
| purM | speG | HMPREF0758_2591 | HMPREF0758_2589 | Phosphoribosylformylglycinamidine cyclo-ligase; COG: COG0150; Pfam: PF00586,PF02769; InterPro: IPR004733. | Diamine N-acetyltransferase; COG: COG1670; Pfam: PF00583; InterPro: IPR016181. | 0.455 |
| purN | IucD | HMPREF0758_2590 | HMPREF0758_0364 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | Hypothetical protein; COG: COG3486; 1.14.13.59. | 0.428 |
| purN | purM | HMPREF0758_2590 | HMPREF0758_2591 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | Phosphoribosylformylglycinamidine cyclo-ligase; COG: COG0150; Pfam: PF00586,PF02769; InterPro: IPR004733. | 0.999 |
| purN | speG | HMPREF0758_2590 | HMPREF0758_2589 | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | Diamine N-acetyltransferase; COG: COG1670; Pfam: PF00583; InterPro: IPR016181. | 0.470 |