| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE95030.1 | yffB | HMPREF0758_3464 | HMPREF0758_2610 | Hypothetical protein; COG: COG2983; Pfam: PF03692; InterPro: IPR008228; Belongs to the UPF0260 family. | Transcriptional regulator, Spx/MgsR family; COG: COG1393; Pfam: PF03960; InterPro: IPR012335; Belongs to the ArsC family. | 0.484 |
| EFE95752.1 | EFE95756.1 | HMPREF0758_2607 | HMPREF0758_2611 | Hypothetical protein. | Hypothetical protein. | 0.549 |
| EFE95752.1 | dapE | HMPREF0758_2607 | HMPREF0758_2609 | Hypothetical protein. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.790 |
| EFE95752.1 | vanY | HMPREF0758_2607 | HMPREF0758_2608 | Hypothetical protein. | Serine-type D-Ala-D-Ala carboxypeptidase; COG: COG1876; Pfam: PF02557; InterPro: IPR003709. | 0.790 |
| EFE95752.1 | yffB | HMPREF0758_2607 | HMPREF0758_2610 | Hypothetical protein. | Transcriptional regulator, Spx/MgsR family; COG: COG1393; Pfam: PF03960; InterPro: IPR012335; Belongs to the ArsC family. | 0.802 |
| EFE95756.1 | EFE95752.1 | HMPREF0758_2611 | HMPREF0758_2607 | Hypothetical protein. | Hypothetical protein. | 0.549 |
| EFE95756.1 | dapE | HMPREF0758_2611 | HMPREF0758_2609 | Hypothetical protein. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.549 |
| EFE95756.1 | vanY | HMPREF0758_2611 | HMPREF0758_2608 | Hypothetical protein. | Serine-type D-Ala-D-Ala carboxypeptidase; COG: COG1876; Pfam: PF02557; InterPro: IPR003709. | 0.549 |
| EFE95756.1 | yffB | HMPREF0758_2611 | HMPREF0758_2610 | Hypothetical protein. | Transcriptional regulator, Spx/MgsR family; COG: COG1393; Pfam: PF03960; InterPro: IPR012335; Belongs to the ArsC family. | 0.549 |
| dapE | EFE95752.1 | HMPREF0758_2609 | HMPREF0758_2607 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Hypothetical protein. | 0.790 |
| dapE | EFE95756.1 | HMPREF0758_2609 | HMPREF0758_2611 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Hypothetical protein. | 0.549 |
| dapE | vanY | HMPREF0758_2609 | HMPREF0758_2608 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Serine-type D-Ala-D-Ala carboxypeptidase; COG: COG1876; Pfam: PF02557; InterPro: IPR003709. | 0.794 |
| dapE | yffB | HMPREF0758_2609 | HMPREF0758_2610 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Transcriptional regulator, Spx/MgsR family; COG: COG1393; Pfam: PF03960; InterPro: IPR012335; Belongs to the ArsC family. | 0.820 |
| hslO | yffB | HMPREF0758_1036 | HMPREF0758_2610 | Chaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | Transcriptional regulator, Spx/MgsR family; COG: COG1393; Pfam: PF03960; InterPro: IPR012335; Belongs to the ArsC family. | 0.487 |
| rpoA | rpoC | HMPREF0758_0937 | HMPREF0758_1663 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA | yffB | HMPREF0758_0937 | HMPREF0758_2610 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcriptional regulator, Spx/MgsR family; COG: COG1393; Pfam: PF03960; InterPro: IPR012335; Belongs to the ArsC family. | 0.589 |
| rpoC | rpoA | HMPREF0758_1663 | HMPREF0758_0937 | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoC | yffB | HMPREF0758_1663 | HMPREF0758_2610 | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcriptional regulator, Spx/MgsR family; COG: COG1393; Pfam: PF03960; InterPro: IPR012335; Belongs to the ArsC family. | 0.491 |
| vanY | EFE95752.1 | HMPREF0758_2608 | HMPREF0758_2607 | Serine-type D-Ala-D-Ala carboxypeptidase; COG: COG1876; Pfam: PF02557; InterPro: IPR003709. | Hypothetical protein. | 0.790 |
| vanY | EFE95756.1 | HMPREF0758_2608 | HMPREF0758_2611 | Serine-type D-Ala-D-Ala carboxypeptidase; COG: COG1876; Pfam: PF02557; InterPro: IPR003709. | Hypothetical protein. | 0.549 |