STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
entCIsochorismate synthase; COG: COG1169; Pfam: PF00425; InterPro: IPR004561. (400 aa)    
Predicted Functional Partners:
entB
Isochorismatase; COG: COG1535; Pfam: PF00857,PF00550; InterPro: IPR000868.
 
 
 0.999
entF
AMP-binding enzyme; COG: COG1020; Pfam: PF00668,PF00501,PF00550,PF00975; InterPro: IPR010071.
 
  
 0.989
entE
(2,3-dihydroxybenzoyl)adenylate synthase; COG: COG1021; Pfam: PF00501; InterPro: IPR011963.
 
  
 0.987
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 0.975
trpG2
Glutamine amidotransferase, class I; COG: COG0512; Pfam: PF00117; InterPro: IPR006221.
 
 0.949
entA
2,3-dihydroxybenzoate-2,3-dehydrogenase; COG: COG1028; Pfam: PF00106; InterPro: IPR016040.
 
  
 0.927
menF
Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
  
  
 
0.927
pheA
Chorismate mutase; COG: COG0077; Pfam: PF01817,PF00800; InterPro: IPR001086.
 
 
 0.911
ubiC
Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
     
 0.909
tyrA
Chorismate mutase; COG: COG0287; Pfam: PF01817,PF02153; InterPro: IPR003099.
  
 
 0.900
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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