| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ctc | rplD | HMPREF0758_2860 | HMPREF0758_0960 | Ribosomal L25p family protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.972 |
| ctc | yfcN | HMPREF0758_2860 | HMPREF0758_2725 | Ribosomal L25p family protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. | Smr domain protein; COG: COG2840; Pfam: PF01713; InterPro: IPR002625; Belongs to the UPF0115 family. | 0.572 |
| cvpA | metJ | HMPREF0758_2761 | HMPREF0758_1162 | CvpA family protein; COG: COG1286; Pfam: PF02674; InterPro: IPR003825. | Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.582 |
| cvpA | mutH | HMPREF0758_2761 | HMPREF0758_2293 | CvpA family protein; COG: COG1286; Pfam: PF02674; InterPro: IPR003825. | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.488 |
| cvpA | yfcN | HMPREF0758_2761 | HMPREF0758_2725 | CvpA family protein; COG: COG1286; Pfam: PF02674; InterPro: IPR003825. | Smr domain protein; COG: COG2840; Pfam: PF01713; InterPro: IPR002625; Belongs to the UPF0115 family. | 0.562 |
| cvpA | ygfZ | HMPREF0758_2761 | HMPREF0758_2227 | CvpA family protein; COG: COG1286; Pfam: PF02674; InterPro: IPR003825. | Folate-binding protein YgfZ; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.558 |
| lptD | ttg2D | HMPREF0758_0550 | HMPREF0758_1862 | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | Toluene tolerance protein Ttg2D; COG: COG2854; Pfam: PF05494; InterPro: IPR008869. | 0.690 |
| lptD | yfcN | HMPREF0758_0550 | HMPREF0758_2725 | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | Smr domain protein; COG: COG2840; Pfam: PF01713; InterPro: IPR002625; Belongs to the UPF0115 family. | 0.639 |
| lptD | ygfZ | HMPREF0758_0550 | HMPREF0758_2227 | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | Folate-binding protein YgfZ; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.454 |
| metJ | cvpA | HMPREF0758_1162 | HMPREF0758_2761 | Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | CvpA family protein; COG: COG1286; Pfam: PF02674; InterPro: IPR003825. | 0.582 |
| metJ | mutH | HMPREF0758_1162 | HMPREF0758_2293 | Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.753 |
| metJ | rraB | HMPREF0758_1162 | HMPREF0758_0750 | Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.751 |
| metJ | ttg2D | HMPREF0758_1162 | HMPREF0758_1862 | Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Toluene tolerance protein Ttg2D; COG: COG2854; Pfam: PF05494; InterPro: IPR008869. | 0.461 |
| metJ | yfcN | HMPREF0758_1162 | HMPREF0758_2725 | Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Smr domain protein; COG: COG2840; Pfam: PF01713; InterPro: IPR002625; Belongs to the UPF0115 family. | 0.654 |
| mutH | cvpA | HMPREF0758_2293 | HMPREF0758_2761 | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | CvpA family protein; COG: COG1286; Pfam: PF02674; InterPro: IPR003825. | 0.488 |
| mutH | metJ | HMPREF0758_2293 | HMPREF0758_1162 | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.753 |
| mutH | rraB | HMPREF0758_2293 | HMPREF0758_0750 | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.745 |
| mutH | ttg2D | HMPREF0758_2293 | HMPREF0758_1862 | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | Toluene tolerance protein Ttg2D; COG: COG2854; Pfam: PF05494; InterPro: IPR008869. | 0.529 |
| mutH | yfcN | HMPREF0758_2293 | HMPREF0758_2725 | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | Smr domain protein; COG: COG2840; Pfam: PF01713; InterPro: IPR002625; Belongs to the UPF0115 family. | 0.611 |
| prmB | rplD | HMPREF0758_2726 | HMPREF0758_0960 | (glutamine-N5) methyltransferase, ribosomal protein L3-specific; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.473 |