| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE95528.1 | EFE95529.1 | HMPREF0758_2730 | HMPREF0758_2731 | Hypothetical protein; COG: COG3101; Pfam: PF04315; InterPro: IPR007411. | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | 0.712 |
| EFE95528.1 | YfcA | HMPREF0758_2730 | HMPREF0758_2729 | Hypothetical protein; COG: COG3101; Pfam: PF04315; InterPro: IPR007411. | Hypothetical protein; COG: COG0730; Pfam: PF01925; InterPro: IPR002781. | 0.733 |
| EFE95528.1 | aroC | HMPREF0758_2730 | HMPREF0758_2727 | Hypothetical protein; COG: COG3101; Pfam: PF04315; InterPro: IPR007411. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.551 |
| EFE95528.1 | mepA | HMPREF0758_2730 | HMPREF0758_2728 | Hypothetical protein; COG: COG3101; Pfam: PF04315; InterPro: IPR007411. | Peptidoglycan amidase MepA; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. | 0.618 |
| EFE95529.1 | EFE95528.1 | HMPREF0758_2731 | HMPREF0758_2730 | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | Hypothetical protein; COG: COG3101; Pfam: PF04315; InterPro: IPR007411. | 0.712 |
| EFE95529.1 | YfcA | HMPREF0758_2731 | HMPREF0758_2729 | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | Hypothetical protein; COG: COG0730; Pfam: PF01925; InterPro: IPR002781. | 0.562 |
| EFE95529.1 | aroC | HMPREF0758_2731 | HMPREF0758_2727 | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.495 |
| EFE95529.1 | mepA | HMPREF0758_2731 | HMPREF0758_2728 | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | Peptidoglycan amidase MepA; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. | 0.551 |
| YfcA | EFE95528.1 | HMPREF0758_2729 | HMPREF0758_2730 | Hypothetical protein; COG: COG0730; Pfam: PF01925; InterPro: IPR002781. | Hypothetical protein; COG: COG3101; Pfam: PF04315; InterPro: IPR007411. | 0.733 |
| YfcA | EFE95529.1 | HMPREF0758_2729 | HMPREF0758_2731 | Hypothetical protein; COG: COG0730; Pfam: PF01925; InterPro: IPR002781. | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | 0.562 |
| YfcA | aroC | HMPREF0758_2729 | HMPREF0758_2727 | Hypothetical protein; COG: COG0730; Pfam: PF01925; InterPro: IPR002781. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.705 |
| YfcA | mepA | HMPREF0758_2729 | HMPREF0758_2728 | Hypothetical protein; COG: COG0730; Pfam: PF01925; InterPro: IPR002781. | Peptidoglycan amidase MepA; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. | 0.945 |
| YfcA | pheT | HMPREF0758_2729 | HMPREF0758_3979 | Hypothetical protein; COG: COG0730; Pfam: PF01925; InterPro: IPR002781. | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Pfam: PF01588,PF03483,PF03484,PF03147; InterPro: IPR004532; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.487 |
| YfcA | prmB | HMPREF0758_2729 | HMPREF0758_2726 | Hypothetical protein; COG: COG0730; Pfam: PF01925; InterPro: IPR002781. | (glutamine-N5) methyltransferase, ribosomal protein L3-specific; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. | 0.467 |
| aroC | EFE95528.1 | HMPREF0758_2727 | HMPREF0758_2730 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Hypothetical protein; COG: COG3101; Pfam: PF04315; InterPro: IPR007411. | 0.551 |
| aroC | EFE95529.1 | HMPREF0758_2727 | HMPREF0758_2731 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | YfcL protein; Pfam: PF08891; InterPro: IPR014987. | 0.495 |
| aroC | YfcA | HMPREF0758_2727 | HMPREF0758_2729 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Hypothetical protein; COG: COG0730; Pfam: PF01925; InterPro: IPR002781. | 0.705 |
| aroC | mepA | HMPREF0758_2727 | HMPREF0758_2728 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Peptidoglycan amidase MepA; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. | 0.730 |
| aroC | pheT | HMPREF0758_2727 | HMPREF0758_3979 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Pfam: PF01588,PF03483,PF03484,PF03147; InterPro: IPR004532; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.652 |
| aroC | prmB | HMPREF0758_2727 | HMPREF0758_2726 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | (glutamine-N5) methyltransferase, ribosomal protein L3-specific; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. | 0.626 |