| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adhC | fghA | HMPREF0758_4597 | HMPREF0758_4598 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COG: COG1062; Pfam: PF08240,PF00107; InterPro: IPR014183; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.999 |
| adhC | yfcG | HMPREF0758_4597 | HMPREF0758_2770 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COG: COG1062; Pfam: PF08240,PF00107; InterPro: IPR014183; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987; Belongs to the GST superfamily. | 0.471 |
| fghA | adhC | HMPREF0758_4598 | HMPREF0758_4597 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COG: COG1062; Pfam: PF08240,PF00107; InterPro: IPR014183; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.999 |
| fghA | yfcE | HMPREF0758_4598 | HMPREF0758_2771 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | Phosphodiesterase family protein; COG: COG0622; Pfam: PF00149; InterPro: IPR000979. | 0.458 |
| fghA | yfcG | HMPREF0758_4598 | HMPREF0758_2770 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987; Belongs to the GST superfamily. | 0.431 |
| folB-2 | sulA | HMPREF0758_2769 | HMPREF0758_2768 | Dihydroneopterin aldolase; COG: COG1539; Pfam: PF02152; InterPro: IPR006157. | TIGR01777 family protein; COG: COG1090; Pfam: PF01370,PF08338; InterPro: IPR010099. | 0.728 |
| folB-2 | yfcG | HMPREF0758_2769 | HMPREF0758_2770 | Dihydroneopterin aldolase; COG: COG1539; Pfam: PF02152; InterPro: IPR006157. | Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987; Belongs to the GST superfamily. | 0.521 |
| gst3 | lysS | HMPREF0758_3085 | HMPREF0758_2239 | Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987. | lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.442 |
| gst3 | rpoA | HMPREF0758_3085 | HMPREF0758_0937 | Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.515 |
| gst3 | yfcG | HMPREF0758_3085 | HMPREF0758_2770 | Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987. | Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987; Belongs to the GST superfamily. | 0.535 |
| lysS | gst3 | HMPREF0758_2239 | HMPREF0758_3085 | lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family. | Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987. | 0.442 |
| lysS | rpoA | HMPREF0758_2239 | HMPREF0758_0937 | lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.586 |
| lysS | rpoZ | HMPREF0758_2239 | HMPREF0758_1279 | lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.436 |
| lysS | yfcG | HMPREF0758_2239 | HMPREF0758_2770 | lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family. | Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987; Belongs to the GST superfamily. | 0.442 |
| rpoA | gst3 | HMPREF0758_0937 | HMPREF0758_3085 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987. | 0.515 |
| rpoA | lysS | HMPREF0758_0937 | HMPREF0758_2239 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.586 |
| rpoA | rpoZ | HMPREF0758_0937 | HMPREF0758_1279 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.996 |
| rpoA | yfcG | HMPREF0758_0937 | HMPREF0758_2770 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987; Belongs to the GST superfamily. | 0.515 |
| rpoZ | lysS | HMPREF0758_1279 | HMPREF0758_2239 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.436 |
| rpoZ | rpoA | HMPREF0758_1279 | HMPREF0758_0937 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.996 |