STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfcEPhosphodiesterase family protein; COG: COG0622; Pfam: PF00149; InterPro: IPR000979. (183 aa)    
Predicted Functional Partners:
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.794
mutT2
Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086.
  
    0.674
EFE93285.1
Hypothetical protein; Pfam: PF05785; InterPro: IPR008430.
    
 
 0.674
YcdZ
Hypothetical protein; Pfam: PF06496; InterPro: IPR009476.
  
     0.571
CsrD
Diguanylate cyclase (GGDEF) domain protein; Pfam: PF00990,PF00563; InterPro: IPR001633.
 
  
 0.471
fghA
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
  
  
 0.458
yfcG
Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987; Belongs to the GST superfamily.
       0.456
YcdX
Putative hydrolase; COG: COG1387; Pfam: PF02811; InterPro: IPR004013; Belongs to the PHP family.
 
    0.435
actP
Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757.
     
 0.414
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.