| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aad | accB | HMPREF0758_3517 | HMPREF0758_1809 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.923 |
| aad | aceB | HMPREF0758_3517 | HMPREF0758_1682 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Malate synthase A; COG: COG2225; Pfam: PF01274; InterPro: IPR001465; Belongs to the malate synthase family. | 0.917 |
| aad | aceF-2 | HMPREF0758_3517 | HMPREF0758_2139 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.928 |
| aad | ackA | HMPREF0758_3517 | HMPREF0758_2780 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.546 |
| aad | acsA | HMPREF0758_3517 | HMPREF0758_0920 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | acetate--CoA ligase; COG: COG0365; Pfam: PF00501; InterPro: IPR011904. | 0.945 |
| aad | nifJ | HMPREF0758_3517 | HMPREF0758_3621 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.972 |
| aad | pflB | HMPREF0758_3517 | HMPREF0758_4438 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR005949. | 0.981 |
| aad | pflD | HMPREF0758_3517 | HMPREF0758_1624 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR010098. | 0.965 |
| aad | pflD2 | HMPREF0758_3517 | HMPREF0758_3003 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR010098. | 0.962 |
| aad | pta | HMPREF0758_3517 | HMPREF0758_2779 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.950 |
| accB | aad | HMPREF0758_1809 | HMPREF0758_3517 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.923 |
| accB | aceB | HMPREF0758_1809 | HMPREF0758_1682 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Malate synthase A; COG: COG2225; Pfam: PF01274; InterPro: IPR001465; Belongs to the malate synthase family. | 0.908 |
| accB | aceF-2 | HMPREF0758_1809 | HMPREF0758_2139 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.915 |
| accB | acsA | HMPREF0758_1809 | HMPREF0758_0920 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | acetate--CoA ligase; COG: COG0365; Pfam: PF00501; InterPro: IPR011904. | 0.907 |
| accB | nifJ | HMPREF0758_1809 | HMPREF0758_3621 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.946 |
| accB | pflB | HMPREF0758_1809 | HMPREF0758_4438 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR005949. | 0.900 |
| accB | pflD | HMPREF0758_1809 | HMPREF0758_1624 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR010098. | 0.900 |
| accB | pflD2 | HMPREF0758_1809 | HMPREF0758_3003 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR010098. | 0.900 |
| accB | pta | HMPREF0758_1809 | HMPREF0758_2779 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.939 |
| aceB | aad | HMPREF0758_1682 | HMPREF0758_3517 | Malate synthase A; COG: COG2225; Pfam: PF01274; InterPro: IPR001465; Belongs to the malate synthase family. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.917 |