| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AldB_2 | ackA | HMPREF0758_3719 | HMPREF0758_2780 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.917 |
| AldB_2 | acsA | HMPREF0758_3719 | HMPREF0758_0920 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | acetate--CoA ligase; COG: COG0365; Pfam: PF00501; InterPro: IPR011904. | 0.929 |
| AldB_2 | feaB-2 | HMPREF0758_3719 | HMPREF0758_3767 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | 0.916 |
| AldB_2 | hpaE | HMPREF0758_3719 | HMPREF0758_0656 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; COG: COG1012; Pfam: PF00171; InterPro: IPR011985; Belongs to the aldehyde dehydrogenase family. | 0.912 |
| AldB_2 | poxB | HMPREF0758_3719 | HMPREF0758_4467 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | Thiamine pyrophosphate enzyme, N-terminal TPP binding domain protein; COG: COG0028; Pfam: PF02776,PF00205,PF02775; InterPro: IPR012001; Belongs to the TPP enzyme family. | 0.904 |
| AldB_2 | yccX | HMPREF0758_3719 | HMPREF0758_4325 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | Acylphosphatase; COG: COG1254; Pfam: PF00708; InterPro: IPR001792. | 0.902 |
| aceA | aceB | HMPREF0758_1683 | HMPREF0758_1682 | Isocitrate lyase; COG: COG2224; Pfam: PF00463; InterPro: IPR015813. | Malate synthase A; COG: COG2225; Pfam: PF01274; InterPro: IPR001465; Belongs to the malate synthase family. | 0.999 |
| aceA | ackA | HMPREF0758_1683 | HMPREF0758_2780 | Isocitrate lyase; COG: COG2224; Pfam: PF00463; InterPro: IPR015813. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.792 |
| aceA | acsA | HMPREF0758_1683 | HMPREF0758_0920 | Isocitrate lyase; COG: COG2224; Pfam: PF00463; InterPro: IPR015813. | acetate--CoA ligase; COG: COG0365; Pfam: PF00501; InterPro: IPR011904. | 0.435 |
| aceA | maeB | HMPREF0758_1683 | HMPREF0758_2637 | Isocitrate lyase; COG: COG2224; Pfam: PF00463; InterPro: IPR015813. | Malate dehydrogenase (oxaloacetate-decarboxylating); COG: COG0281; Pfam: PF00390,PF03949,PF01515; InterPro: IPR002505. | 0.777 |
| aceA | pta | HMPREF0758_1683 | HMPREF0758_2779 | Isocitrate lyase; COG: COG2224; Pfam: PF00463; InterPro: IPR015813. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.729 |
| aceB | aceA | HMPREF0758_1682 | HMPREF0758_1683 | Malate synthase A; COG: COG2225; Pfam: PF01274; InterPro: IPR001465; Belongs to the malate synthase family. | Isocitrate lyase; COG: COG2224; Pfam: PF00463; InterPro: IPR015813. | 0.999 |
| aceB | ackA | HMPREF0758_1682 | HMPREF0758_2780 | Malate synthase A; COG: COG2225; Pfam: PF01274; InterPro: IPR001465; Belongs to the malate synthase family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.765 |
| aceB | acsA | HMPREF0758_1682 | HMPREF0758_0920 | Malate synthase A; COG: COG2225; Pfam: PF01274; InterPro: IPR001465; Belongs to the malate synthase family. | acetate--CoA ligase; COG: COG0365; Pfam: PF00501; InterPro: IPR011904. | 0.957 |
| aceB | maeB | HMPREF0758_1682 | HMPREF0758_2637 | Malate synthase A; COG: COG2225; Pfam: PF01274; InterPro: IPR001465; Belongs to the malate synthase family. | Malate dehydrogenase (oxaloacetate-decarboxylating); COG: COG0281; Pfam: PF00390,PF03949,PF01515; InterPro: IPR002505. | 0.976 |
| aceB | pta | HMPREF0758_1682 | HMPREF0758_2779 | Malate synthase A; COG: COG2225; Pfam: PF01274; InterPro: IPR001465; Belongs to the malate synthase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.971 |
| ackA | AldB_2 | HMPREF0758_2780 | HMPREF0758_3719 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | 0.917 |
| ackA | aceA | HMPREF0758_2780 | HMPREF0758_1683 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Isocitrate lyase; COG: COG2224; Pfam: PF00463; InterPro: IPR015813. | 0.792 |
| ackA | aceB | HMPREF0758_2780 | HMPREF0758_1682 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Malate synthase A; COG: COG2225; Pfam: PF01274; InterPro: IPR001465; Belongs to the malate synthase family. | 0.765 |
| ackA | acsA | HMPREF0758_2780 | HMPREF0758_0920 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | acetate--CoA ligase; COG: COG0365; Pfam: PF00501; InterPro: IPR011904. | 0.930 |