| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| YcdZ | dcuC | HMPREF0758_2811 | HMPREF0758_4574 | Hypothetical protein; Pfam: PF06496; InterPro: IPR009476. | Transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family; COG: COG3069; Pfam: PF03606; InterPro: IPR004669. | 0.670 |
| YcdZ | menC | HMPREF0758_2811 | HMPREF0758_2820 | Hypothetical protein; Pfam: PF06496; InterPro: IPR009476. | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.568 |
| YcdZ | tex | HMPREF0758_2811 | HMPREF0758_3339 | Hypothetical protein; Pfam: PF06496; InterPro: IPR009476. | ASCH domain protein; COG: COG3097; Pfam: PF06164; InterPro: IPR008314; Belongs to the UPF0267 family. | 0.742 |
| YcdZ | tyrP | HMPREF0758_2811 | HMPREF0758_2825 | Hypothetical protein; Pfam: PF06496; InterPro: IPR009476. | Aromatic amino acid transport protein; COG: COG0814; Pfam: PF03222; InterPro: IPR002091. | 0.657 |
| YcdZ | yfbU | HMPREF0758_2811 | HMPREF0758_2782 | Hypothetical protein; Pfam: PF06496; InterPro: IPR009476. | YfbU domain protein; COG: COG3013; Pfam: PF03887; InterPro: IPR005587; Belongs to the UPF0304 family. | 0.704 |
| cinA2 | tyrP | HMPREF0758_2826 | HMPREF0758_2825 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | Aromatic amino acid transport protein; COG: COG0814; Pfam: PF03222; InterPro: IPR002091. | 0.495 |
| dcuC | YcdZ | HMPREF0758_4574 | HMPREF0758_2811 | Transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family; COG: COG3069; Pfam: PF03606; InterPro: IPR004669. | Hypothetical protein; Pfam: PF06496; InterPro: IPR009476. | 0.670 |
| dcuC | menC | HMPREF0758_4574 | HMPREF0758_2820 | Transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family; COG: COG3069; Pfam: PF03606; InterPro: IPR004669. | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.551 |
| dcuC | tex | HMPREF0758_4574 | HMPREF0758_3339 | Transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family; COG: COG3069; Pfam: PF03606; InterPro: IPR004669. | ASCH domain protein; COG: COG3097; Pfam: PF06164; InterPro: IPR008314; Belongs to the UPF0267 family. | 0.641 |
| dcuC | tyrP | HMPREF0758_4574 | HMPREF0758_2825 | Transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family; COG: COG3069; Pfam: PF03606; InterPro: IPR004669. | Aromatic amino acid transport protein; COG: COG0814; Pfam: PF03222; InterPro: IPR002091. | 0.463 |
| dcuC | yfbU | HMPREF0758_4574 | HMPREF0758_2782 | Transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family; COG: COG3069; Pfam: PF03606; InterPro: IPR004669. | YfbU domain protein; COG: COG3013; Pfam: PF03887; InterPro: IPR005587; Belongs to the UPF0304 family. | 0.517 |
| glpT | tyrP | HMPREF0758_1553 | HMPREF0758_2825 | Glycerol-3-phosphate transporter; COG: COG2271; Pfam: PF07690; InterPro: IPR005267. | Aromatic amino acid transport protein; COG: COG0814; Pfam: PF03222; InterPro: IPR002091. | 0.418 |
| menC | YcdZ | HMPREF0758_2820 | HMPREF0758_2811 | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | Hypothetical protein; Pfam: PF06496; InterPro: IPR009476. | 0.568 |
| menC | dcuC | HMPREF0758_2820 | HMPREF0758_4574 | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | Transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family; COG: COG3069; Pfam: PF03606; InterPro: IPR004669. | 0.551 |
| menC | tex | HMPREF0758_2820 | HMPREF0758_3339 | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | ASCH domain protein; COG: COG3097; Pfam: PF06164; InterPro: IPR008314; Belongs to the UPF0267 family. | 0.547 |
| menC | trpR | HMPREF0758_2820 | HMPREF0758_0599 | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | 0.401 |
| menC | tyrP | HMPREF0758_2820 | HMPREF0758_2825 | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | Aromatic amino acid transport protein; COG: COG0814; Pfam: PF03222; InterPro: IPR002091. | 0.565 |
| menC | yfbU | HMPREF0758_2820 | HMPREF0758_2782 | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | YfbU domain protein; COG: COG3013; Pfam: PF03887; InterPro: IPR005587; Belongs to the UPF0304 family. | 0.672 |
| putA | tyrP | HMPREF0758_3240 | HMPREF0758_2825 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Aromatic amino acid transport protein; COG: COG0814; Pfam: PF03222; InterPro: IPR002091. | 0.438 |
| tex | YcdZ | HMPREF0758_3339 | HMPREF0758_2811 | ASCH domain protein; COG: COG3097; Pfam: PF06164; InterPro: IPR008314; Belongs to the UPF0267 family. | Hypothetical protein; Pfam: PF06496; InterPro: IPR009476. | 0.742 |