| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE97991.1 | cinA2 | HMPREF0758_0319 | HMPREF0758_2826 | Hypothetical protein; COG: COG1073; Pfam: PF06500; InterPro: IPR010520; 3.1.-.-; Belongs to the UPF0255 family. | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | 0.418 |
| NorM | cinA2 | HMPREF0758_2944 | HMPREF0758_2826 | MATE efflux family protein; COG: COG0534; Pfam: PF01554; InterPro: IPR002528. | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | 0.434 |
| cinA | cinA2 | HMPREF0758_0427 | HMPREF0758_2826 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | 0.932 |
| cinA | nadD | HMPREF0758_0427 | HMPREF0758_4913 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.950 |
| cinA | nadE | HMPREF0758_0427 | HMPREF0758_2475 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.495 |
| cinA | pgsA | HMPREF0758_0427 | HMPREF0758_4263 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.437 |
| cinA | rec | HMPREF0758_0427 | HMPREF0758_4381 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.443 |
| cinA | recA | HMPREF0758_0427 | HMPREF0758_0426 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.647 |
| cinA2 | EFE97991.1 | HMPREF0758_2826 | HMPREF0758_0319 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | Hypothetical protein; COG: COG1073; Pfam: PF06500; InterPro: IPR010520; 3.1.-.-; Belongs to the UPF0255 family. | 0.418 |
| cinA2 | NorM | HMPREF0758_2826 | HMPREF0758_2944 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | MATE efflux family protein; COG: COG0534; Pfam: PF01554; InterPro: IPR002528. | 0.434 |
| cinA2 | cinA | HMPREF0758_2826 | HMPREF0758_0427 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | 0.932 |
| cinA2 | cinA3 | HMPREF0758_2826 | HMPREF0758_4233 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | 0.447 |
| cinA2 | nadD | HMPREF0758_2826 | HMPREF0758_4913 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.497 |
| cinA2 | nadE | HMPREF0758_2826 | HMPREF0758_2475 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.493 |
| cinA2 | pgsA | HMPREF0758_2826 | HMPREF0758_4263 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.625 |
| cinA2 | rec | HMPREF0758_2826 | HMPREF0758_4381 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.429 |
| cinA2 | recA | HMPREF0758_2826 | HMPREF0758_0426 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.471 |
| cinA2 | tyrP | HMPREF0758_2826 | HMPREF0758_2825 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | Aromatic amino acid transport protein; COG: COG0814; Pfam: PF03222; InterPro: IPR002091. | 0.495 |
| cinA3 | cinA2 | HMPREF0758_4233 | HMPREF0758_2826 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | 0.447 |
| cinA3 | nadD | HMPREF0758_4233 | HMPREF0758_4913 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.510 |