| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aad | gltA | HMPREF0758_3517 | HMPREF0758_4848 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family. | 0.448 |
| aad | grcA | HMPREF0758_3517 | HMPREF0758_2443 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | 0.751 |
| aad | nifJ | HMPREF0758_3517 | HMPREF0758_3621 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.977 |
| aad | pflA | HMPREF0758_3517 | HMPREF0758_3004 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Glycyl-radical enzyme activating protein family protein; COG: COG1180; Pfam: PF04055; InterPro: IPR012839. | 0.753 |
| aad | pflA-2 | HMPREF0758_3517 | HMPREF0758_4439 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.833 |
| aad | pflC | HMPREF0758_3517 | HMPREF0758_1623 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Radical SAM domain protein; COG: COG1180; Pfam: PF04055. | 0.794 |
| aad | pflD2 | HMPREF0758_3517 | HMPREF0758_3003 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR010098. | 0.790 |
| aad | pta | HMPREF0758_3517 | HMPREF0758_2779 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.962 |
| gltA | aad | HMPREF0758_4848 | HMPREF0758_3517 | Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.448 |
| gltA | nifJ | HMPREF0758_4848 | HMPREF0758_3621 | Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family. | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | 0.968 |
| gltA | pflD2 | HMPREF0758_4848 | HMPREF0758_3003 | Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR010098. | 0.534 |
| gltA | pta | HMPREF0758_4848 | HMPREF0758_2779 | Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.621 |
| grcA | aad | HMPREF0758_2443 | HMPREF0758_3517 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.751 |
| grcA | pflA | HMPREF0758_2443 | HMPREF0758_3004 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Glycyl-radical enzyme activating protein family protein; COG: COG1180; Pfam: PF04055; InterPro: IPR012839. | 0.772 |
| grcA | pflA-2 | HMPREF0758_2443 | HMPREF0758_4439 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.781 |
| grcA | pflC | HMPREF0758_2443 | HMPREF0758_1623 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Radical SAM domain protein; COG: COG1180; Pfam: PF04055. | 0.774 |
| grcA | pflD2 | HMPREF0758_2443 | HMPREF0758_3003 | Glycine radical domain protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. | Formate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR010098. | 0.811 |
| nifJ | aad | HMPREF0758_3621 | HMPREF0758_3517 | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1454; Pfam: PF00171,PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.977 |
| nifJ | gltA | HMPREF0758_3621 | HMPREF0758_4848 | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family. | 0.968 |
| nifJ | pflA | HMPREF0758_3621 | HMPREF0758_3004 | Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895. | Glycyl-radical enzyme activating protein family protein; COG: COG1180; Pfam: PF04055; InterPro: IPR012839. | 0.652 |