STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcm-2DNA (cytosine-5-)-methyltransferase; COG: COG0270; Pfam: PF00145; InterPro: IPR001525; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (354 aa)    
Predicted Functional Partners:
dcm
DNA (cytosine-5-)-methyltransferase; COG: COG0270; Pfam: PF00145; InterPro: IPR001525; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
  
  0.958
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.919
expI
Autoinducer synthetase; Pfam: PF00765; InterPro: IPR016181.
  
  
 0.913
EFE95384.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Pfam: PF02518; InterPro: IPR003594.
 
     0.907
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...]
    
  0.902
lasI
Acyl-homoserine-lactone synthase; COG: COG3916; Pfam: PF00765; InterPro: IPR016181.
     
 0.901
speD
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
     
  0.900
EFE95385.1
Hypothetical protein.
       0.785
EFE95382.1
Hypothetical protein.
       0.534
YdjM
Putative membrane-bound metal-dependent hydrolase; COG: COG1988; Pfam: PF04307; InterPro: IPR007404.
   
    0.499
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.