| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cheA | cheB | HMPREF0758_3185 | HMPREF0758_3190 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0643; Pfam: PF01627,PF09078,PF02895,PF02518,PF01584; InterPro: IPR003594. | Response regulator receiver domain protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | 0.999 |
| cheA | cheR | HMPREF0758_3185 | HMPREF0758_3189 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0643; Pfam: PF01627,PF09078,PF02895,PF02518,PF01584; InterPro: IPR003594. | CheR methyltransferase, SAM binding domain protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. | 0.971 |
| cheA | cheW | HMPREF0758_3185 | HMPREF0758_3186 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0643; Pfam: PF01627,PF09078,PF02895,PF02518,PF01584; InterPro: IPR003594. | CheW-like protein; COG: COG0835; Pfam: PF01584; InterPro: IPR002545. | 0.999 |
| cheA | cheY-2 | HMPREF0758_3185 | HMPREF0758_3191 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0643; Pfam: PF01627,PF09078,PF02895,PF02518,PF01584; InterPro: IPR003594. | Chemotaxis protein CheY; COG: COG0784; Pfam: PF00072; InterPro: IPR001789. | 0.975 |
| cheA | cheZ | HMPREF0758_3185 | HMPREF0758_3192 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0643; Pfam: PF01627,PF09078,PF02895,PF02518,PF01584; InterPro: IPR003594. | Chemotaxis protein CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). | 0.986 |
| cheA | flgJ | HMPREF0758_3185 | HMPREF0758_3207 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0643; Pfam: PF01627,PF09078,PF02895,PF02518,PF01584; InterPro: IPR003594. | Flagellar rod assembly protein/muramidase FlgJ; COG: COG1705; Pfam: PF01832; InterPro: IPR013377. | 0.459 |
| cheA | fliJ | HMPREF0758_3185 | HMPREF0758_3218 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0643; Pfam: PF01627,PF09078,PF02895,PF02518,PF01584; InterPro: IPR003594. | Flagellar export protein FliJ; Flagellar protein that affects chemotactic events. Belongs to the FliJ family. | 0.591 |
| cheA | fliM | HMPREF0758_3185 | HMPREF0758_3215 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0643; Pfam: PF01627,PF09078,PF02895,PF02518,PF01584; InterPro: IPR003594. | Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | 0.968 |
| cheA | motA | HMPREF0758_3185 | HMPREF0758_3183 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0643; Pfam: PF01627,PF09078,PF02895,PF02518,PF01584; InterPro: IPR003594. | Flagellar motor stator protein MotA; COG: COG1291. | 0.982 |
| cheA | motB | HMPREF0758_3185 | HMPREF0758_3184 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0643; Pfam: PF01627,PF09078,PF02895,PF02518,PF01584; InterPro: IPR003594. | OmpA family protein; COG: COG1360; Pfam: PF00691; InterPro: IPR006665. | 0.991 |
| cheB | cheA | HMPREF0758_3190 | HMPREF0758_3185 | Response regulator receiver domain protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0643; Pfam: PF01627,PF09078,PF02895,PF02518,PF01584; InterPro: IPR003594. | 0.999 |
| cheB | cheR | HMPREF0758_3190 | HMPREF0758_3189 | Response regulator receiver domain protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | CheR methyltransferase, SAM binding domain protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. | 0.999 |
| cheB | cheW | HMPREF0758_3190 | HMPREF0758_3186 | Response regulator receiver domain protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | CheW-like protein; COG: COG0835; Pfam: PF01584; InterPro: IPR002545. | 0.999 |
| cheB | cheY-2 | HMPREF0758_3190 | HMPREF0758_3191 | Response regulator receiver domain protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | Chemotaxis protein CheY; COG: COG0784; Pfam: PF00072; InterPro: IPR001789. | 0.878 |
| cheB | cheZ | HMPREF0758_3190 | HMPREF0758_3192 | Response regulator receiver domain protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | Chemotaxis protein CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). | 0.949 |
| cheB | flgJ | HMPREF0758_3190 | HMPREF0758_3207 | Response regulator receiver domain protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | Flagellar rod assembly protein/muramidase FlgJ; COG: COG1705; Pfam: PF01832; InterPro: IPR013377. | 0.469 |
| cheB | fliJ | HMPREF0758_3190 | HMPREF0758_3218 | Response regulator receiver domain protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | Flagellar export protein FliJ; Flagellar protein that affects chemotactic events. Belongs to the FliJ family. | 0.636 |
| cheB | fliM | HMPREF0758_3190 | HMPREF0758_3215 | Response regulator receiver domain protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | 0.924 |
| cheB | motA | HMPREF0758_3190 | HMPREF0758_3183 | Response regulator receiver domain protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | Flagellar motor stator protein MotA; COG: COG1291. | 0.756 |
| cheB | motB | HMPREF0758_3190 | HMPREF0758_3184 | Response regulator receiver domain protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | OmpA family protein; COG: COG1360; Pfam: PF00691; InterPro: IPR006665. | 0.790 |