STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliSFlagellar protein FliS; COG: COG1516; Pfam: PF02561; InterPro: IPR003713. (136 aa)    
Predicted Functional Partners:
fliC
Flagellin D3 domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.998
fliD
Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
 
 0.997
flgL
Flagellar hook-associated protein 3; COG: COG1344; Pfam: PF00669; InterPro: IPR013384.
 
 
 0.996
flgK
Flagellar hook-associated protein FlgK; COG: COG1256; Pfam: PF00460,PF06429; InterPro: IPR002371.
 
 
 0.992
fliI
Flagellar protein export ATPase FliI; COG: COG1157; Pfam: PF00006; InterPro: IPR005714.
 
 
 0.988
fliT
Flagellar protein FliT; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
  
  
 0.986
flhA
Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
 
 
 0.985
flgC
Flagellar basal-body rod protein FlgC; COG: COG1558; Pfam: PF00460,PF06429; InterPro: IPR006299; Belongs to the flagella basal body rod proteins family.
 
  
 0.984
fliE
Flagellar hook-basal body complex protein FliE; COG: COG1677; Pfam: PF02049; InterPro: IPR001624.
 
 
 0.984
fliM
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
  
 0.982
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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