STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliZFlagellar regulatory protein FliZ; Pfam: PF02899. (165 aa)    
Predicted Functional Partners:
fliA
Flagellar biosynthesis sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
  
  
 0.950
flgK
Flagellar hook-associated protein FlgK; COG: COG1256; Pfam: PF00460,PF06429; InterPro: IPR002371.
   
   0.822
flgB
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
  
 0.773
fliD
Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.771
fliT
Flagellar protein FliT; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
  
  
 0.763
fliC
Flagellin D3 domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
  
  
 0.746
flgM
Flagellar biosynthesis anti-sigma factor FlgM; COG: COG2747; Pfam: PF04316; InterPro: IPR007412.
   
  
 0.738
flgN
FlgN protein; COG: COG3418; Pfam: PF05130; InterPro: IPR007809.
   
  
 0.731
flgD
Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.
   
    0.719
fliS
Flagellar protein FliS; COG: COG1516; Pfam: PF02561; InterPro: IPR003713.
  
  
 0.699
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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