| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE95108.1 | mviN | HMPREF0758_3162 | HMPREF0758_3410 | Type VI secretion system FHA domain protein. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.635 |
| ftsI | ftsW | HMPREF0758_0520 | HMPREF0758_0514 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.961 |
| ftsI | mrdB | HMPREF0758_0520 | HMPREF0758_4917 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.855 |
| ftsI | murA | HMPREF0758_0520 | HMPREF0758_1866 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.648 |
| ftsI | murD | HMPREF0758_0520 | HMPREF0758_0515 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.871 |
| ftsI | murF | HMPREF0758_0520 | HMPREF0758_0517 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.903 |
| ftsI | murG | HMPREF0758_0520 | HMPREF0758_0513 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.859 |
| ftsI | mviN | HMPREF0758_0520 | HMPREF0758_3410 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.546 |
| ftsW | ftsI | HMPREF0758_0514 | HMPREF0758_0520 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | 0.961 |
| ftsW | mrdB | HMPREF0758_0514 | HMPREF0758_4917 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.410 |
| ftsW | murA | HMPREF0758_0514 | HMPREF0758_1866 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.843 |
| ftsW | murD | HMPREF0758_0514 | HMPREF0758_0515 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.975 |
| ftsW | murF | HMPREF0758_0514 | HMPREF0758_0517 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.981 |
| ftsW | murG | HMPREF0758_0514 | HMPREF0758_0513 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.988 |
| ftsW | mviN | HMPREF0758_0514 | HMPREF0758_3410 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.589 |
| mrdB | ftsI | HMPREF0758_4917 | HMPREF0758_0520 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | 0.855 |
| mrdB | ftsW | HMPREF0758_4917 | HMPREF0758_0514 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.410 |
| mrdB | murA | HMPREF0758_4917 | HMPREF0758_1866 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.841 |
| mrdB | murD | HMPREF0758_4917 | HMPREF0758_0515 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.883 |
| mrdB | murF | HMPREF0758_4917 | HMPREF0758_0517 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.857 |