| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94981.1 | cutC | HMPREF0758_3415 | HMPREF0758_3414 | HPP family protein; COG: COG3448; Pfam: PF04982; InterPro: IPR007065. | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | 0.450 |
| Exo_I | cutC | HMPREF0758_0755 | HMPREF0758_3414 | Glycosyl hydrolase family 20, catalytic domain protein; COG: COG3525; Pfam: PF02838,PF00728; InterPro: IPR013781. | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | 0.504 |
| Exo_I | nagE | HMPREF0758_0755 | HMPREF0758_4886 | Glycosyl hydrolase family 20, catalytic domain protein; COG: COG3525; Pfam: PF02838,PF00728; InterPro: IPR013781. | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367,PF00358; InterPro: IPR010974. | 0.975 |
| Opd | cutC | HMPREF0758_0310 | HMPREF0758_3414 | Phosphotriesterase family protein; COG: COG1735; Pfam: PF02126; InterPro: IPR001559. | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | 0.470 |
| PatB | cutC | HMPREF0758_3413 | HMPREF0758_3414 | Aminotransferase, class I/II; COG: COG1168; Pfam: PF00155; InterPro: IPR004839. | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | 0.573 |
| actP | cutC | HMPREF0758_0141 | HMPREF0758_3414 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | 0.525 |
| agaS | cutC | HMPREF0758_2967 | HMPREF0758_3414 | Sugar isomerase, AgaS family; COG: COG2222; Pfam: PF01380. | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | 0.468 |
| agaS | nagA | HMPREF0758_2967 | HMPREF0758_4888 | Sugar isomerase, AgaS family; COG: COG2222; Pfam: PF01380. | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | 0.766 |
| cutC | EFE94981.1 | HMPREF0758_3414 | HMPREF0758_3415 | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | HPP family protein; COG: COG3448; Pfam: PF04982; InterPro: IPR007065. | 0.450 |
| cutC | Exo_I | HMPREF0758_3414 | HMPREF0758_0755 | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Glycosyl hydrolase family 20, catalytic domain protein; COG: COG3525; Pfam: PF02838,PF00728; InterPro: IPR013781. | 0.504 |
| cutC | Opd | HMPREF0758_3414 | HMPREF0758_0310 | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Phosphotriesterase family protein; COG: COG1735; Pfam: PF02126; InterPro: IPR001559. | 0.470 |
| cutC | PatB | HMPREF0758_3414 | HMPREF0758_3413 | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Aminotransferase, class I/II; COG: COG1168; Pfam: PF00155; InterPro: IPR004839. | 0.573 |
| cutC | actP | HMPREF0758_3414 | HMPREF0758_0141 | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | 0.525 |
| cutC | agaS | HMPREF0758_3414 | HMPREF0758_2967 | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Sugar isomerase, AgaS family; COG: COG2222; Pfam: PF01380. | 0.468 |
| cutC | metK | HMPREF0758_3414 | HMPREF0758_2175 | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.536 |
| cutC | nagA | HMPREF0758_3414 | HMPREF0758_4888 | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | 0.499 |
| cutC | nagB | HMPREF0758_3414 | HMPREF0758_4887 | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.675 |
| cutC | nagE | HMPREF0758_3414 | HMPREF0758_4886 | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367,PF00358; InterPro: IPR010974. | 0.476 |
| metK | cutC | HMPREF0758_2175 | HMPREF0758_3414 | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | 0.536 |
| nagA | agaS | HMPREF0758_4888 | HMPREF0758_2967 | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | Sugar isomerase, AgaS family; COG: COG2222; Pfam: PF01380. | 0.766 |