| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE95004.1 | hexR | HMPREF0758_3438 | HMPREF0758_3437 | Hypothetical protein. | Transcriptional regulator, RpiR family; COG: COG1737; Pfam: PF01418,PF01380; InterPro: IPR001347. | 0.561 |
| EFE95004.1 | zwf | HMPREF0758_3438 | HMPREF0758_3439 | Hypothetical protein. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.445 |
| arbF | hexR | HMPREF0758_1477 | HMPREF0758_3437 | PTS system, beta-glucoside-specific, IIABC component; COG: COG1263; Pfam: PF00367,PF02378,PF00358; InterPro: IPR011297. | Transcriptional regulator, RpiR family; COG: COG1737; Pfam: PF01418,PF01380; InterPro: IPR001347. | 0.409 |
| arbF | nagE | HMPREF0758_1477 | HMPREF0758_4886 | PTS system, beta-glucoside-specific, IIABC component; COG: COG1263; Pfam: PF00367,PF02378,PF00358; InterPro: IPR011297. | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367,PF00358; InterPro: IPR010974. | 0.969 |
| arbF | pyk | HMPREF0758_1477 | HMPREF0758_3436 | PTS system, beta-glucoside-specific, IIABC component; COG: COG1263; Pfam: PF00367,PF02378,PF00358; InterPro: IPR011297. | Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family. | 0.503 |
| arbF | zwf | HMPREF0758_1477 | HMPREF0758_3439 | PTS system, beta-glucoside-specific, IIABC component; COG: COG1263; Pfam: PF00367,PF02378,PF00358; InterPro: IPR011297. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.487 |
| eda-2 | eda-3 | HMPREF0758_1685 | HMPREF0758_3441 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | KHG/KDPG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | 0.900 |
| eda-2 | edd | HMPREF0758_1685 | HMPREF0758_1686 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.992 |
| eda-2 | hexR | HMPREF0758_1685 | HMPREF0758_3437 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Transcriptional regulator, RpiR family; COG: COG1737; Pfam: PF01418,PF01380; InterPro: IPR001347. | 0.423 |
| eda-2 | pyk | HMPREF0758_1685 | HMPREF0758_3436 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family. | 0.829 |
| eda-2 | zwf | HMPREF0758_1685 | HMPREF0758_3439 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.723 |
| eda-3 | eda-2 | HMPREF0758_3441 | HMPREF0758_1685 | KHG/KDPG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | 0.900 |
| eda-3 | edd | HMPREF0758_3441 | HMPREF0758_1686 | KHG/KDPG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.984 |
| eda-3 | hexR | HMPREF0758_3441 | HMPREF0758_3437 | KHG/KDPG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Transcriptional regulator, RpiR family; COG: COG1737; Pfam: PF01418,PF01380; InterPro: IPR001347. | 0.550 |
| eda-3 | pyk | HMPREF0758_3441 | HMPREF0758_3436 | KHG/KDPG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family. | 0.856 |
| eda-3 | zwf | HMPREF0758_3441 | HMPREF0758_3439 | KHG/KDPG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.850 |
| edd | eda-2 | HMPREF0758_1686 | HMPREF0758_1685 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | 0.992 |
| edd | eda-3 | HMPREF0758_1686 | HMPREF0758_3441 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | KHG/KDPG aldolase; COG: COG0800; Pfam: PF01081; InterPro: IPR013785. | 0.984 |
| edd | hexR | HMPREF0758_1686 | HMPREF0758_3437 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Transcriptional regulator, RpiR family; COG: COG1737; Pfam: PF01418,PF01380; InterPro: IPR001347. | 0.434 |
| edd | zwf | HMPREF0758_1686 | HMPREF0758_3439 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.928 |