| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE96416.1 | edd | HMPREF0758_1845 | HMPREF0758_1686 | Hypothetical protein; COG: COG2706; InterPro: IPR015943. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.900 |
| EFE96416.1 | gnd | HMPREF0758_1845 | HMPREF0758_4542 | Hypothetical protein; COG: COG2706; InterPro: IPR015943. | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.929 |
| EFE96416.1 | pgl | HMPREF0758_1845 | HMPREF0758_4804 | Hypothetical protein; COG: COG2706; InterPro: IPR015943. | Putative 6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. | 0.928 |
| EFE96416.1 | zwf | HMPREF0758_1845 | HMPREF0758_3439 | Hypothetical protein; COG: COG2706; InterPro: IPR015943. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.917 |
| edd | EFE96416.1 | HMPREF0758_1686 | HMPREF0758_1845 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Hypothetical protein; COG: COG2706; InterPro: IPR015943. | 0.900 |
| edd | gap | HMPREF0758_1686 | HMPREF0758_3492 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.509 |
| edd | glk | HMPREF0758_1686 | HMPREF0758_2698 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucokinase; COG: COG0837; Pfam: PF02685; InterPro: IPR003836; Belongs to the bacterial glucokinase family. | 0.783 |
| edd | gnd | HMPREF0758_1686 | HMPREF0758_4542 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.923 |
| edd | pgi | HMPREF0758_1686 | HMPREF0758_1693 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.453 |
| edd | pgl | HMPREF0758_1686 | HMPREF0758_4804 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Putative 6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. | 0.900 |
| edd | zwf | HMPREF0758_1686 | HMPREF0758_3439 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.928 |
| gap | edd | HMPREF0758_3492 | HMPREF0758_1686 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.509 |
| gap | pgi | HMPREF0758_3492 | HMPREF0758_1693 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.951 |
| gap | pyk | HMPREF0758_3492 | HMPREF0758_3436 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family. | 0.706 |
| gap | tpiA | HMPREF0758_3492 | HMPREF0758_1181 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.996 |
| gap | zwf | HMPREF0758_3492 | HMPREF0758_3439 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.896 |
| glk | edd | HMPREF0758_2698 | HMPREF0758_1686 | Glucokinase; COG: COG0837; Pfam: PF02685; InterPro: IPR003836; Belongs to the bacterial glucokinase family. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.783 |
| glk | pgi | HMPREF0758_2698 | HMPREF0758_1693 | Glucokinase; COG: COG0837; Pfam: PF02685; InterPro: IPR003836; Belongs to the bacterial glucokinase family. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.940 |
| glk | pgm | HMPREF0758_2698 | HMPREF0758_4874 | Glucokinase; COG: COG0837; Pfam: PF02685; InterPro: IPR003836; Belongs to the bacterial glucokinase family. | Phosphoglucomutase, alpha-D-glucose phosphate-specific; COG: COG0033; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR005852. | 0.920 |
| glk | zwf | HMPREF0758_2698 | HMPREF0758_3439 | Glucokinase; COG: COG0837; Pfam: PF02685; InterPro: IPR003836; Belongs to the bacterial glucokinase family. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.946 |