| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LsrF | eno | HMPREF0758_3362 | HMPREF0758_0472 | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.833 |
| LsrF | fba2 | HMPREF0758_3362 | HMPREF0758_3848 | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | 0.912 |
| LsrF | fbaA | HMPREF0758_3362 | HMPREF0758_2200 | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.912 |
| LsrF | fbaB | HMPREF0758_3362 | HMPREF0758_2556 | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | 0.900 |
| LsrF | gap | HMPREF0758_3362 | HMPREF0758_3492 | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.914 |
| LsrF | pgi | HMPREF0758_3362 | HMPREF0758_1693 | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.828 |
| LsrF | tkt | HMPREF0758_3362 | HMPREF0758_5114 | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.715 |
| LsrF | tpiA | HMPREF0758_3362 | HMPREF0758_1181 | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.923 |
| LsrF | zwf | HMPREF0758_3362 | HMPREF0758_3439 | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.810 |
| eno | LsrF | HMPREF0758_0472 | HMPREF0758_3362 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | 0.833 |
| eno | fba2 | HMPREF0758_0472 | HMPREF0758_3848 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | 0.940 |
| eno | fbaA | HMPREF0758_0472 | HMPREF0758_2200 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.940 |
| eno | fbaB | HMPREF0758_0472 | HMPREF0758_2556 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | 0.833 |
| eno | gap | HMPREF0758_0472 | HMPREF0758_3492 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.906 |
| eno | pgi | HMPREF0758_0472 | HMPREF0758_1693 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.977 |
| eno | pgk | HMPREF0758_0472 | HMPREF0758_2199 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. | 0.988 |
| eno | tkt | HMPREF0758_0472 | HMPREF0758_5114 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.920 |
| eno | tpiA | HMPREF0758_0472 | HMPREF0758_1181 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.982 |
| eno | zwf | HMPREF0758_0472 | HMPREF0758_3439 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.869 |
| fba2 | LsrF | HMPREF0758_3848 | HMPREF0758_3362 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785. | 0.912 |