| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE95061.1 | EFE97364.1 | HMPREF0758_3495 | HMPREF0758_0977 | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | Hypothetical protein; COG: COG3529; InterPro: IPR012658. | 0.721 |
| EFE95061.1 | fadB | HMPREF0758_3495 | HMPREF0758_1645 | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.596 |
| EFE95061.1 | miaE | HMPREF0758_3495 | HMPREF0758_0749 | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | tRNA-(ms[2]io[6]A)-hydroxylase; COG: COG4445; Pfam: PF06175; InterPro: IPR010386. | 0.692 |
| EFE95061.1 | msrB | HMPREF0758_3495 | HMPREF0758_3494 | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | methionine-R-sulfoxide reductase; COG: COG0229; Pfam: PF01641; InterPro: IPR002579; Belongs to the MsrB Met sulfoxide reductase family. | 0.969 |
| EFE95061.1 | sdhC | HMPREF0758_3495 | HMPREF0758_4847 | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | Succinate dehydrogenase, cytochrome b556 subunit; COG: COG2009; Pfam: PF01127; InterPro: IPR014314; overlaps another CDS with the same product name. | 0.680 |
| EFE95061.1 | sdhD | HMPREF0758_3495 | HMPREF0758_4846 | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.772 |
| EFE95061.1 | topA-2 | HMPREF0758_3495 | HMPREF0758_3559 | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.536 |
| EFE95061.1 | ycgL | HMPREF0758_3495 | HMPREF0758_3460 | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | YcgL domain protein; COG: COG3100; Pfam: PF05166; InterPro: IPR007840. | 0.542 |
| EFE95061.1 | ygfY | HMPREF0758_3495 | HMPREF0758_2228 | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | TPR repeat region; COG: COG2938; Pfam: PF03937; InterPro: IPR005631. | 0.672 |
| EFE95061.1 | yhgI | HMPREF0758_3495 | HMPREF0758_1052 | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.690 |
| EFE97364.1 | EFE95061.1 | HMPREF0758_0977 | HMPREF0758_3495 | Hypothetical protein; COG: COG3529; InterPro: IPR012658. | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | 0.721 |
| EFE97364.1 | miaE | HMPREF0758_0977 | HMPREF0758_0749 | Hypothetical protein; COG: COG3529; InterPro: IPR012658. | tRNA-(ms[2]io[6]A)-hydroxylase; COG: COG4445; Pfam: PF06175; InterPro: IPR010386. | 0.555 |
| EFE97364.1 | sdhC | HMPREF0758_0977 | HMPREF0758_4847 | Hypothetical protein; COG: COG3529; InterPro: IPR012658. | Succinate dehydrogenase, cytochrome b556 subunit; COG: COG2009; Pfam: PF01127; InterPro: IPR014314; overlaps another CDS with the same product name. | 0.441 |
| EFE97364.1 | sdhD | HMPREF0758_0977 | HMPREF0758_4846 | Hypothetical protein; COG: COG3529; InterPro: IPR012658. | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.521 |
| fadB | EFE95061.1 | HMPREF0758_1645 | HMPREF0758_3495 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | 0.596 |
| fadB | sdhC | HMPREF0758_1645 | HMPREF0758_4847 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | Succinate dehydrogenase, cytochrome b556 subunit; COG: COG2009; Pfam: PF01127; InterPro: IPR014314; overlaps another CDS with the same product name. | 0.678 |
| fadB | topA-2 | HMPREF0758_1645 | HMPREF0758_3559 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.436 |
| miaE | EFE95061.1 | HMPREF0758_0749 | HMPREF0758_3495 | tRNA-(ms[2]io[6]A)-hydroxylase; COG: COG4445; Pfam: PF06175; InterPro: IPR010386. | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | 0.692 |
| miaE | EFE97364.1 | HMPREF0758_0749 | HMPREF0758_0977 | tRNA-(ms[2]io[6]A)-hydroxylase; COG: COG4445; Pfam: PF06175; InterPro: IPR010386. | Hypothetical protein; COG: COG3529; InterPro: IPR012658. | 0.555 |
| miaE | sdhD | HMPREF0758_0749 | HMPREF0758_4846 | tRNA-(ms[2]io[6]A)-hydroxylase; COG: COG4445; Pfam: PF06175; InterPro: IPR010386. | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.594 |