STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
TonBTonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (250 aa)    
Predicted Functional Partners:
fhuA
TonB-dependent siderophore receptor; COG: COG1629; Pfam: PF07715,PF00593; InterPro: IPR010105.
 
 
 0.953
exbB
tonB-system energizer ExbB; COG: COG0811; Pfam: PF01618; InterPro: IPR014164.
  
 
 0.892
exbD
TonB system transport protein ExbD; COG: COG0848; Pfam: PF02472; InterPro: IPR003400.
 
 
 0.889
ExbD_1
Transport energizing protein, ExbD/TolR family; COG: COG0848; Pfam: PF02472; InterPro: IPR003400.
 
 
 0.878
tolR
Putative protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
 
 0.849
btuB
TonB-dependent vitamin B12 receptor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
 
 
 
 0.821
fepA
TonB-dependent siderophore receptor; COG: COG4771; Pfam: PF07715,PF00593; InterPro: IPR010105.
 
 
 0.821
yncD
TonB-dependent receptor; COG: COG1629; Pfam: PF07715,PF00593; InterPro: IPR000531.
 
 
 0.817
fhuE
TonB-dependent siderophore receptor; COG: COG4773; Pfam: PF07715,PF00593; InterPro: IPR010105.
  
 
 0.767
tolQ
Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
 
 0.696
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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