STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysBHTH-type transcriptional regulator CysB; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. (324 aa)    
Predicted Functional Partners:
tdrA
LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family.
  
     0.525
hemX
HemX; COG: COG2959; Pfam: PF04375; InterPro: IPR007470.
  
     0.501
AllS_2
LysR substrate binding domain protein; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family.
  
     0.465
DmlR_6
Transcriptional regulator, LysR family; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family.
  
     0.429
DmlR_35
LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family.
  
     0.427
DmlR_33
LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family.
  
     0.415
GltR_2
LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family.
  
     0.407
EFE94687.1
DNA topoisomerase I; COG: COG0550; Pfam: PF01751.
  
    0.405
topA-2
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.405
lysR7
LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family.
  
     0.401
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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