| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BvgS_2 | arcB | HMPREF0758_3254 | HMPREF0758_1880 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | PAS domain S-box protein; COG: COG0642; Pfam: PF00989,PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | 0.984 |
| BvgS_2 | evgS | HMPREF0758_3254 | HMPREF0758_2028 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | Response regulator receiver domain protein; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR001638. | 0.982 |
| BvgS_2 | fnr | HMPREF0758_3254 | HMPREF0758_3646 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | Cyclic nucleotide-binding domain protein; COG: COG0664; Pfam: PF00027,PF00325; InterPro: IPR014710. | 0.606 |
| BvgS_2 | hemN | HMPREF0758_3254 | HMPREF0758_1300 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | Coproporphyrinogen dehydrogenase; COG: COG0635; Pfam: PF04055,PF06969; InterPro: IPR004558; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.494 |
| BvgS_2 | rpoB | HMPREF0758_3254 | HMPREF0758_1662 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.438 |
| BvgS_2 | rpoC | HMPREF0758_3254 | HMPREF0758_1663 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.461 |
| BvgS_2 | rpoZ | HMPREF0758_3254 | HMPREF0758_1279 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.430 |
| BvgS_2 | uspE | HMPREF0758_3254 | HMPREF0758_3645 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | Universal stress family protein; COG: COG0589; Pfam: PF00582; InterPro: IPR014729. | 0.448 |
| arcB | BvgS_2 | HMPREF0758_1880 | HMPREF0758_3254 | PAS domain S-box protein; COG: COG0642; Pfam: PF00989,PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | 0.984 |
| arcB | evgS | HMPREF0758_1880 | HMPREF0758_2028 | PAS domain S-box protein; COG: COG0642; Pfam: PF00989,PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Response regulator receiver domain protein; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR001638. | 0.985 |
| arcB | fnr | HMPREF0758_1880 | HMPREF0758_3646 | PAS domain S-box protein; COG: COG0642; Pfam: PF00989,PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Cyclic nucleotide-binding domain protein; COG: COG0664; Pfam: PF00027,PF00325; InterPro: IPR014710. | 0.612 |
| arcB | rpoB | HMPREF0758_1880 | HMPREF0758_1662 | PAS domain S-box protein; COG: COG0642; Pfam: PF00989,PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.407 |
| arcB | rpoC | HMPREF0758_1880 | HMPREF0758_1663 | PAS domain S-box protein; COG: COG0642; Pfam: PF00989,PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.436 |
| evgS | BvgS_2 | HMPREF0758_2028 | HMPREF0758_3254 | Response regulator receiver domain protein; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR001638. | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | 0.982 |
| evgS | arcB | HMPREF0758_2028 | HMPREF0758_1880 | Response regulator receiver domain protein; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR001638. | PAS domain S-box protein; COG: COG0642; Pfam: PF00989,PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | 0.985 |
| evgS | fnr | HMPREF0758_2028 | HMPREF0758_3646 | Response regulator receiver domain protein; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR001638. | Cyclic nucleotide-binding domain protein; COG: COG0664; Pfam: PF00027,PF00325; InterPro: IPR014710. | 0.548 |
| evgS | rpoZ | HMPREF0758_2028 | HMPREF0758_1279 | Response regulator receiver domain protein; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR001638. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.412 |
| fnr | BvgS_2 | HMPREF0758_3646 | HMPREF0758_3254 | Cyclic nucleotide-binding domain protein; COG: COG0664; Pfam: PF00027,PF00325; InterPro: IPR014710. | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | 0.606 |
| fnr | arcB | HMPREF0758_3646 | HMPREF0758_1880 | Cyclic nucleotide-binding domain protein; COG: COG0664; Pfam: PF00027,PF00325; InterPro: IPR014710. | PAS domain S-box protein; COG: COG0642; Pfam: PF00989,PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | 0.612 |
| fnr | evgS | HMPREF0758_3646 | HMPREF0758_2028 | Cyclic nucleotide-binding domain protein; COG: COG0664; Pfam: PF00027,PF00325; InterPro: IPR014710. | Response regulator receiver domain protein; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR001638. | 0.548 |