STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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Coexpression
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[Homology]
Score
ycgRType IV pilus assembly protein PilZ; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility. (238 aa)    
Predicted Functional Partners:
gmr
RNase II stability modulator; COG: COG2202.
 
  
 0.753
fliS
Flagellar protein FliS; COG: COG1516; Pfam: PF02561; InterPro: IPR003713.
  
  
 0.735
fliD
Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
    0.695
fliM
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
 
 0.694
motA
Flagellar motor stator protein MotA; COG: COG1291.
 
   0.685
flgK
Flagellar hook-associated protein FlgK; COG: COG1256; Pfam: PF00460,PF06429; InterPro: IPR002371.
  
  
 0.657
mdoC
Acyltransferase; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
  
     0.652
flgN
FlgN protein; COG: COG3418; Pfam: PF05130; InterPro: IPR007809.
  
  
 0.641
flgM
Flagellar biosynthesis anti-sigma factor FlgM; COG: COG2747; Pfam: PF04316; InterPro: IPR007412.
  
  
 0.639
motB
OmpA family protein; COG: COG1360; Pfam: PF00691; InterPro: IPR006665.
 
 
 0.635
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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