| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CmtR | FecI | HMPREF0758_3797 | HMPREF0758_3710 | Transcriptional regulator, ArsR family; COG: COG0640; Pfam: PF01022; InterPro: IPR011991. | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | 0.650 |
| EFE94838.1 | FecI | HMPREF0758_3709 | HMPREF0758_3710 | Alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | 0.940 |
| EFE95963.1 | FecI | HMPREF0758_2401 | HMPREF0758_3710 | Alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | 0.729 |
| FecI | CmtR | HMPREF0758_3710 | HMPREF0758_3797 | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | Transcriptional regulator, ArsR family; COG: COG0640; Pfam: PF01022; InterPro: IPR011991. | 0.650 |
| FecI | EFE94838.1 | HMPREF0758_3710 | HMPREF0758_3709 | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | Alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.940 |
| FecI | EFE95963.1 | HMPREF0758_3710 | HMPREF0758_2401 | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | Alkylhydroperoxidase AhpD family core domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.729 |
| FecI | cheR | HMPREF0758_3710 | HMPREF0758_3189 | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | CheR methyltransferase, SAM binding domain protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. | 0.632 |
| FecI | mclA | HMPREF0758_3710 | HMPREF0758_2448 | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | Anti sigma-E protein RseA domain protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic pro [...] | 0.870 |
| FecI | rpoA | HMPREF0758_3710 | HMPREF0758_0937 | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.687 |
| FecI | rpoB | HMPREF0758_3710 | HMPREF0758_1662 | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.687 |
| FecI | rpoC | HMPREF0758_3710 | HMPREF0758_1663 | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.696 |
| FecI | rpoZ | HMPREF0758_3710 | HMPREF0758_1279 | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.678 |
| FecI | soxR2 | HMPREF0758_3710 | HMPREF0758_4057 | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | Transcriptional regulator, MerR family; COG: COG0789; Pfam: PF00376,PF09278; InterPro: IPR000551. | 0.564 |
| cheR | FecI | HMPREF0758_3189 | HMPREF0758_3710 | CheR methyltransferase, SAM binding domain protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | 0.632 |
| mclA | FecI | HMPREF0758_2448 | HMPREF0758_3710 | Anti sigma-E protein RseA domain protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic pro [...] | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | 0.870 |
| rpoA | FecI | HMPREF0758_0937 | HMPREF0758_3710 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | 0.687 |
| rpoA | rpoB | HMPREF0758_0937 | HMPREF0758_1662 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA | rpoC | HMPREF0758_0937 | HMPREF0758_1663 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA | rpoZ | HMPREF0758_0937 | HMPREF0758_1279 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.996 |
| rpoB | FecI | HMPREF0758_1662 | HMPREF0758_3710 | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Sigma-70 region 2; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. | 0.687 |